FAM110A and MYOG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM110A	MYOG
Description		family with sequence similarity 110 member A	myogenin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Spindle Microtubule Cell Cortex	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Protein-DNA Complex
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Chromatin DNA Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Mitotic Spindle Organization	Ossification Regulation Of DNA-templated Transcription Muscle Organ Development Skeletal Muscle Tissue Development Negative Regulation Of Cell Population Proliferation Tissue Development Positive Regulation Of Myotube Differentiation Positive Regulation Of Muscle Atrophy Regulation Of Skeletal Muscle Satellite Cell Proliferation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Striated Muscle Atrophy Response To Denervation Involved In Regulation Of Muscle Adaptation Myotube Differentiation Cell Differentiation Skeletal Muscle Cell Differentiation Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Myoblast Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Development Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Cell Cycle Cellular Response To Lithium Ion Cellular Response To Tumor Necrosis Factor Cellular Response To Growth Factor Stimulus Cellular Response To Estradiol Stimulus Regulation Of Myoblast Fusion
Pathways			Myogenesis Myogenesis TGFBR3 expression
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Prostate cancer ( 31562322)	Asthma ( 30929738 31959851) Asthma (childhood onset) ( 30929738)
Interacting Genes		52 interacting genes: AGR2 BICD2 CCNDBP1 CDR2 COG4 COG6 CSNK1E CTDSP1 CTNNA3 DYNC1I1 EFEMP1 EFEMP2 FHL3 FSD2 GOLGA2 GOLGA6L9 HOOK2 HSF2BP KRT15 KRT27 KRT31 KRT34 KRT37 KRT38 KRT39 KRTAP10-8 LDOC1 LIX1 MEIS3 MIF4GD MKRN3 MTUS2 MYOG PFDN5 PNMA1 PYGM RASSF10 RASSF3 RCN1 RINT1 ROPN1 STX11 TCF4 TRIM23 TRIM27 TRIM54 TRIM69 TSC1 TSG101 USHBP1 VPS52 ZSCAN4	62 interacting genes: ABI2 BBS4 BFSP2 BHLHA15 CALM1 CALM2 CALM3 CARM1 CCDC120 CCDC28A CDH18 CFAP53 CFTR CLUAP1 CPSF4 CSRP3 CTNNA3 EIF4E2 FAM110A FAM90A1 FBXO32 FBXO7 FIGLA FTL GEM H2AP HNF1A ID1 ID2 ID3 IKBIP IL16 KLHL42 LAMTOR5 LMO3 MAPK3 MAPKBP1 MBD3 MDFI MEF2A MEF2C MLH1 NEK6 ODAD4 PACRGL POLR2C POLR2J PRMT5 SEPTIN5 SP1 SPG21 SRF TAF6L TCF3 TLE5 TRIM43 TSSK3 TTC32 TXNDC9 USHBP1 YME1L1 ZCCHC14
Entrez ID		83541	4656
HPRD ID		12775	01167
Ensembl ID		ENSG00000125898	ENSG00000122180
Uniprot IDs		Q9BQ89	P15173
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Structural Molecule Activity Supramolecular Fiber Organization Epithelial Cell Differentiation Protein Binding Tissue Morphogenesis Morphogenesis Of An Epithelium Vesicle-mediated Transport Cytoskeleton Organization Golgi Vesicle Transport Organelle Organization Retrograde Transport, Vesicle Recycling Within Golgi Golgi Transport Complex Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule	Protein Dimerization Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity DNA-binding Transcription Factor Binding Cytoskeleton Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Spindle Pole Protein-containing Complex BHLH Transcription Factor Binding Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Heart Development Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of High Voltage-gated Calcium Channel Activity Titin Binding Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Transcription Regulator Inhibitor Activity Spindle Microtubule Nucleus Detection Of Calcium Ion Cardiac Myofibril Assembly Regulation Of Cell Communication By Electrical Coupling Calcium Channel Regulator Activity Protein Phosphatase Activator Activity Protein Heterodimerization Activity Histone Arginine N-methyltransferase Activity Calyx Of Held Sarcomere E-box Binding Positive Regulation Of Macromolecule Biosynthetic Process Face Development Catalytic Complex Heart Looping Regulation Of Developmental Process Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Heart Contraction Developmental Process Embryonic Heart Tube Morphogenesis Negative Regulation Of Transporter Activity Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Channel Complex Calcineurin-mediated Signaling Positive Regulation Of Biosynthetic Process Lung Morphogenesis Regulation Of B Cell Activation Presynaptic Cytosol Regulation Of Cardiac Muscle Cell Action Potential Response To Calcium Ion Myelin Sheath
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