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HIST1H3E and CHAF1A
Number of citations of the paper that reports this interaction (PMID
15664198
)
71
Data Source:
HPRD
(in vivo, in vitro)
HIST1H3E
CHAF1A
Gene Name
histone cluster 1, H3e
chromatin assembly factor 1, subunit A (p150)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Chromosome
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Membrane
Protein Complex
Extracellular Vesicular Exosome
Nuclear Chromatin
CAF-1 Complex
Protein Complex
Molecular Function
DNA Binding
Protein Binding
Protein Heterodimerization Activity
Chromatin Binding
Protein Binding
Identical Protein Binding
Unfolded Protein Binding
Chromo Shadow Domain Binding
Biological Process
Chromatin Silencing At RDNA
Chromatin Organization
DNA Replication-dependent Nucleosome Assembly
Blood Coagulation
Gene Expression
DNA Methylation On Cytosine
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Silencing
DNA Replication
DNA Repair
DNA Replication-dependent Nucleosome Assembly
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Protein Complex Assembly
Cell Cycle
Chromatin Assembly
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
PKMTs methylate histone lysines
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
HDMs demethylate histones
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
Factors involved in megakaryocyte development and platelet production
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
ASF1A
ASF1B
CHAF1A
CHAF1B
DNMT3A
PHF1
RPS6KA5
SETD1B
TRIM24
UHRF1
37 interactors:
ANP32A
ANP32B
ASF1A
ASF1B
BLM
CBX1
CBX5
CDC7
CDK2
CHAF1B
DBF4
DDX41
HIST1H3E
HIST3H3
HMGB2
LZTR1
MBD1
MSH6
PABPC1
PCBD2
PCNA
RBFOX2
REL
SET
SUMO1
SUMO2
SUMO3
TCERG1
TCF4
TRIM28
XRCC5
XRCC6
YWHAB
YWHAE
YWHAG
YWHAQ
ZNF408
Entrez ID
8353
10036
HPRD ID
11907
03148
Ensembl ID
ENSG00000196966
ENSG00000167670
Uniprot IDs
P68431
Q13111
PDB IDs
1CS9
1CT6
1Q3L
2B2T
2B2U
2B2V
2B2W
2C1J
2C1N
2CV5
2KWJ
2KWK
2L75
2LBM
2M0O
2RI7
2UXN
3A1B
3AFA
3AVR
3AYW
3AZE
3AZF
3AZG
3AZH
3AZI
3AZJ
3AZK
3AZL
3AZM
3AZN
3B95
3KMT
3KQI
3LQI
3LQJ
3O34
3O35
3O37
3RIG
3RIY
3U4S
3U5N
3U5O
3U5P
3UEE
3UEF
3UIG
3UII
3UIK
3V43
3W96
3W97
3W98
3W99
3ZG6
3ZVY
4A0J
4A0N
4A7J
4BD3
4F4U
4F56
4FWF
4HON
4I51
Enriched GO Terms of Interacting Partners
?
Chromatin Organization
DNA Replication-dependent Nucleosome Assembly
Chromosome Organization
Chromatin Modification
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Organelle Organization
Nucleosome Assembly
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Chromatin Assembly
Nucleosome Organization
Gene Expression
Transcription, DNA-templated
Chromatin Assembly Or Disassembly
RNA Biosynthetic Process
Protein-DNA Complex Assembly
DNA Packaging
Regulation Of Gene Expression, Epigenetic
Nucleobase-containing Compound Metabolic Process
DNA Conformation Change
RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
DNA Methylation On Cytosine
Macromolecule Biosynthetic Process
Cellular Response To Stress
Cellular Response To DNA Damage Stimulus
Nitrogen Compound Metabolic Process
DNA Metabolic Process
DNA Repair
Biosynthetic Process
DNA Replication-independent Nucleosome Assembly
Cellular Macromolecular Complex Assembly
Negative Regulation Of Gene Expression
Cellular Metabolic Process
DNA Methylation
Positive Regulation Of Histone Modification
Negative Regulation Of Gene Expression, Epigenetic
Histone H2A-S1 Phosphorylation
Histone Modification
Methylation
Protein Complex Assembly
DNA Modification
Negative Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
DNA Metabolic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
DNA Conformation Change
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
DNA Repair
Protein-DNA Complex Assembly
Chromosome Organization
Nitrogen Compound Metabolic Process
Nucleosome Assembly
DNA Replication-dependent Nucleosome Assembly
Chromatin Assembly
Nucleosome Organization
Cellular Response To DNA Damage Stimulus
Chromatin Assembly Or Disassembly
Regulation Of Cellular Process
Positive Regulation Of Cellular Metabolic Process
DNA Packaging
Positive Regulation Of Metabolic Process
Cellular Response To Stress
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Protein Sumoylation
DNA Recombination
Positive Regulation Of Intracellular Transport
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Response To Stress
Telomere Maintenance
Organelle Organization
DNA Replication
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Protein Complex Assembly
Macromolecule Biosynthetic Process
Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Metabolic Process
Tagcloud
?
3a
aggressive
cohorts
concept
driven
gsea
intact
malignancies
malignancy
mcm3
mcm6
mdm2
multifactorial
networks
neuroblastoma
nutlin
oncogene
opposing
overcome
p53
potently
reciprocally
repressed
repression
rrm2
signature
signatures
subset
worst
Tagcloud (Difference)
?
3a
aggressive
cohorts
concept
driven
gsea
intact
malignancies
malignancy
mcm3
mcm6
mdm2
multifactorial
networks
neuroblastoma
nutlin
oncogene
opposing
overcome
p53
potently
reciprocally
repressed
repression
rrm2
signature
signatures
subset
worst
Tagcloud (Intersection)
?