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HIST1H3E and SETD1B
Number of citations of the paper that reports this interaction (PMID
17355966
)
63
Data Source:
BioGRID
(enzymatic study)
HIST1H3E
SETD1B
Gene Name
histone cluster 1, H3e
SET domain containing 1B
Image
Gene Ontology Annotations
Cellular Component
Nuclear Chromosome
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Membrane
Protein Complex
Extracellular Vesicular Exosome
Nucleoplasm
Chromosome
Cytoplasm
Nuclear Speck
Histone Methyltransferase Complex
Set1C/COMPASS Complex
Molecular Function
DNA Binding
Protein Binding
Protein Heterodimerization Activity
Nucleotide Binding
RNA Binding
Protein Binding
Histone Methyltransferase Activity (H3-K4 Specific)
Biological Process
Chromatin Silencing At RDNA
Chromatin Organization
DNA Replication-dependent Nucleosome Assembly
Blood Coagulation
Gene Expression
DNA Methylation On Cytosine
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Silencing
Chromatin Organization
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Histone H3-K4 Methylation
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
PKMTs methylate histone lysines
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
HDMs demethylate histones
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
Factors involved in megakaryocyte development and platelet production
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Chromatin modifying enzymes
Chromatin organization
PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
ASF1A
ASF1B
CHAF1A
CHAF1B
DNMT3A
PHF1
RPS6KA5
SETD1B
TRIM24
UHRF1
4 interactors:
HIST1H3A
HIST1H3E
HIST2H3C
WDR5
Entrez ID
8353
23067
HPRD ID
11907
19516
Ensembl ID
ENSG00000196966
ENSG00000139718
Uniprot IDs
P68431
F6MFW1
Q9UPS6
PDB IDs
1CS9
1CT6
1Q3L
2B2T
2B2U
2B2V
2B2W
2C1J
2C1N
2CV5
2KWJ
2KWK
2L75
2LBM
2M0O
2RI7
2UXN
3A1B
3AFA
3AVR
3AYW
3AZE
3AZF
3AZG
3AZH
3AZI
3AZJ
3AZK
3AZL
3AZM
3AZN
3B95
3KMT
3KQI
3LQI
3LQJ
3O34
3O35
3O37
3RIG
3RIY
3U4S
3U5N
3U5O
3U5P
3UEE
3UEF
3UIG
3UII
3UIK
3V43
3W96
3W97
3W98
3W99
3ZG6
3ZVY
4A0J
4A0N
4A7J
4BD3
4F4U
4F56
4FWF
4HON
4I51
3UVO
4ES0
Enriched GO Terms of Interacting Partners
?
Chromatin Organization
DNA Replication-dependent Nucleosome Assembly
Chromosome Organization
Chromatin Modification
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Organelle Organization
Nucleosome Assembly
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Chromatin Assembly
Nucleosome Organization
Gene Expression
Transcription, DNA-templated
Chromatin Assembly Or Disassembly
RNA Biosynthetic Process
Protein-DNA Complex Assembly
DNA Packaging
Regulation Of Gene Expression, Epigenetic
Nucleobase-containing Compound Metabolic Process
DNA Conformation Change
RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
DNA Methylation On Cytosine
Macromolecule Biosynthetic Process
Cellular Response To Stress
Cellular Response To DNA Damage Stimulus
Nitrogen Compound Metabolic Process
DNA Metabolic Process
DNA Repair
Biosynthetic Process
DNA Replication-independent Nucleosome Assembly
Cellular Macromolecular Complex Assembly
Negative Regulation Of Gene Expression
Cellular Metabolic Process
DNA Methylation
Positive Regulation Of Histone Modification
Negative Regulation Of Gene Expression, Epigenetic
Histone H2A-S1 Phosphorylation
Histone Modification
Methylation
Protein Complex Assembly
DNA Modification
Negative Regulation Of Transcription, DNA-templated
DNA Methylation On Cytosine
Chromatin Silencing At RDNA
Chromatin Silencing
DNA Methylation
Methylation
Negative Regulation Of Gene Expression, Epigenetic
DNA Modification
Gene Silencing
DNA Replication-dependent Nucleosome Assembly
Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Silencing
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Response To Wounding
Chromatin Organization
Nucleosome Assembly
Chromatin Assembly
Nucleosome Organization
Chromatin Assembly Or Disassembly
Protein-DNA Complex Assembly
Chromosome Organization
DNA Metabolic Process
DNA Packaging
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter
DNA Conformation Change
Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Histone H4-K16 Acetylation
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Gluconeogenesis
Tagcloud
?
11q13
aberrations
adam29
ash1l
assayed
cdkn2a
consortium
crebbp
drinking
ep300
escc
exome
fam135b
histopathological
kmt2c
kmt2d
microrna
mir548k
mll2
mll3
nfe2l2
notch1
oesophageal
pik3ca
rb1
repertoire
sixth
tumorigenic
vast
Tagcloud (Difference)
?
11q13
aberrations
adam29
ash1l
assayed
cdkn2a
consortium
crebbp
drinking
ep300
escc
exome
fam135b
histopathological
kmt2c
kmt2d
microrna
mir548k
mll2
mll3
nfe2l2
notch1
oesophageal
pik3ca
rb1
repertoire
sixth
tumorigenic
vast
Tagcloud (Intersection)
?