SYN2

Description		synapsin II
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Postsynaptic Density Synaptic Vesicle Membrane SNARE Complex Synapse Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function	Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Chemical Synaptic Transmission Neurotransmitter Secretion Calcium-ion Regulated Exocytosis Synapse Organization Synaptic Vesicle Clustering Synaptic Vesicle Cycle
Pathways		Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle
Drugs
Diseases
GWAS		A body shape index ( 34021172) Chronic obstructive pulmonary disease ( 30804561) Circulating leptin levels or type 2 diabetes ( 32341051) Creatinine levels ( 29403010) Eosinophil count ( 32888494) Estimated glomerular filtration rate ( 31152163) Fasting blood insulin (BMI interaction) ( 22581228) Glomerular filtration rate ( 29403010) Glycated hemoglobin levels ( 34059833 28898252) Heel bone mineral density ( 30598549) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Leprosy ( 27976721) Nontraumatic osteonecrosis of the femoral head ( 32701715) Platelet count ( 22139419 29403010) Thyroid stimulating hormone levels ( 32769997 25743335) Triglycerides ( 30275531) Type 2 diabetes ( 18372903) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		7 interacting genes: CHRM4 NOS1AP PRKACA SYN1 SYN3 YWHAE YWHAZ
Entrez ID		6854
HPRD ID		02857
Ensembl ID		ENSG00000157152
Uniprot IDs		B3KRB3 Q59GM1 Q86VA8 Q92777
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Cycle Regulation Of Heart Rate By Chemical Signal Phosphoserine Residue Binding Regulation Of Heart Rate Synaptic Vesicle Clustering Extrinsic Component Of Synaptic Vesicle Membrane Regulation Of Calcium Ion Transmembrane Transport Intracellular Potassium Ion Homeostasis Positive Regulation Of Protein Export From Nucleus Glutamatergic Synapse Regulation Of Heart Contraction Cell Communication Protein Domain Specific Binding Regulation Of Calcium Ion Transport Potassium Ion Homeostasis Regulation Of Blood Circulation Regulation Of Protein Export From Nucleus Establishment Of Localization In Cell Neurotransmitter Secretion Regulation Of Membrane Repolarization Regulation Of Monoatomic Cation Transmembrane Transport Protein Sequestering Activity Regulation Of Monoatomic Ion Transmembrane Transport Ubiquitin Protein Ligase Binding Cellular Response To Heat Chemical Synaptic Transmission Trans-synaptic Signaling Synaptic Signaling Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Metal Ion Transport TORC1 Signaling Negative Regulation Of TORC1 Signaling Regulation Of Potassium Ion Transmembrane Transport Regulation Of Monoatomic Ion Transport Signaling Adaptor Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway TOR Signaling Response To Heat Regulation Of Potassium Ion Transport Negative Regulation Of TOR Signaling Positive Regulation Of Intracellular Protein Transport Protein Kinase Binding Vesicle-mediated Transport In Synapse Organelle Localization Protein Phosphatase Binding Regulation Of TORC1 Signaling Neurotransmitter Transport Melanosome Modulation Of Chemical Synaptic Transmission Regulation Of Heart Rate By Hormone
Tagcloud ?