KDM2B

Gene Name		lysine (K)-specific demethylase 2B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus PcG Protein Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding RRNA Binding Histone Demethylase Activity Histone Demethylase Activity (H3-K36 Specific)
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Spermatogenesis Histone Demethylation Midbrain-hindbrain Boundary Morphogenesis Fourth Ventricle Development Lateral Ventricle Development Third Ventricle Development Initiation Of Neural Tube Closure Forebrain Development Midbrain Development Hindbrain Development Histone H2A Monoubiquitination Negative Regulation Of Neuron Apoptotic Process Embryonic Camera-type Eye Morphogenesis Oxidation-reduction Process Histone H3-K36 Demethylation Negative Regulation Of Neural Precursor Cell Proliferation
Pathways		Chromatin modifying enzymes Chromatin organization HDMs demethylate histones
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CEBPE HIST1H3A LZTR1 UBE2D1
Entrez ID		84678
HPRD ID		12362
Ensembl ID		ENSG00000089094
Uniprot IDs		Q8NHM5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA Replication-dependent Nucleosome Assembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA Methylation On Cytosine Chromatin Silencing At RDNA
Tagcloud ?		7b aberrant analog array axis azacitidine bypassed cd34 cyclopentanyl deazaadenosine di dysregulated dznep ezh2 g0 h3k27 h3k27me3 hypomethylating hypothesized landscape let marrows methylated nanostring p16 preliminary preventing repression tri