QTRT1 and SH3GL3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		QTRT1	SH3GL3
Gene Name		queuine tRNA-ribosyltransferase 1	SH3-domain GRB2-like 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion	Early Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Queuine TRNA-ribosyltransferase Activity Metal Ion Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	TRNA Modification Queuosine Biosynthetic Process	Endocytosis Signal Transduction Central Nervous System Development
Pathways
Drugs
Diseases
GWAS			Height ( 18391950 18391951 20397748)
Protein-Protein Interactions		6 interactors: COPS6 NDUFA4L2 SETDB1 SH3GL3 UNC119 ZBTB16	44 interactors: ADRB1 AES ARHGDIA ARHGEF6 ATXN2 C11orf68 C4orf17 CALCOCO1 CBLC CD101 CRIP1 DNM1 DPPA4 DPYSL4 EGFL6 EMD FAM173A FASLG GABBR2 HTT LRRK2 NDUFB9 PDCD6IP PIAS4 PTPRO QTRT1 RBM48 RER1 RPL35A SEPT8 SH3D19 SH3GL1 SH3GL2 SH3KBP1 SHC3 SNRPN SNX24 SYNJ1 TERF1 TNNT1 TOE1 VIM WASL WDR33
Entrez ID		81890	6457
HPRD ID		17943	04528
Ensembl ID		ENSG00000213339	ENSG00000140600
Uniprot IDs		Q71RF8 Q9BXR0	Q99963
PDB IDs			2EW3 2Z0V
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis Cytokinesis, Completion Of Separation Positive Regulation Of NK T Cell Differentiation Male Germ-line Stem Cell Asymmetric Division Regulation Of Caveolin-mediated Endocytosis Mitotic Cytokinetic Process Cullin Deneddylation Histone H3-K9 Trimethylation Protein Deneddylation Regulation Of Clathrin-mediated Endocytosis Cell Division	Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Signaling Regulation Of ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell-cell Signaling Signal Transduction Vesicle-mediated Transport Cell Communication Movement Of Cell Or Subcellular Component Regulation Of Vesicle-mediated Transport Response To Stimulus Cellular Response To Stimulus Cell Death Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Membrane Organization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Projection Morphogenesis Negative Regulation Of ERBB Signaling Pathway Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Developmental Process System Development Neuron Development Apoptotic Process Cellular Process Generation Of Neurons Actin Filament-based Movement Multicellular Organismal Development Nervous System Development Programmed Cell Death Regulation Of Signaling Neurogenesis Regulation Of Endocytosis Regulation Of Signal Transduction Negative Regulation Of Neuron Differentiation Neuron Projection Development Establishment Of Vesicle Localization Synaptic Transmission Positive Regulation Of Apoptotic Process Cell Projection Morphogenesis Neuron Differentiation Vesicle Localization Response To Growth Factor Axon Guidance Neurotrophin TRK Receptor Signaling Pathway Cell Part Morphogenesis
Tagcloud ?		actb ap1s1 api5 calculating crossbred csn1s2 fabp3 gilts icg lactation ltf mined mrpl39 mtg1 normalization parturition pcsk2 ppp2r5b primiparous ptbp1 qpcr rps15a scd tmem24 trim41 underscore uxt vabp vapb	85k aorta cbl cin85 circulation circulatory cooperation da diameters dorsal endocytosis exerted impairing interacting lumen lumens morpholino morpholinos partner phosphatidylinositol shrinkage shrunken specification stereotyped studying unaffected vasculature zebrafish
Tagcloud (Difference) ?		actb ap1s1 api5 calculating crossbred csn1s2 fabp3 gilts icg lactation ltf mined mrpl39 mtg1 normalization parturition pcsk2 ppp2r5b primiparous ptbp1 qpcr rps15a scd tmem24 trim41 underscore uxt vabp vapb	85k aorta cbl cin85 circulation circulatory cooperation da diameters dorsal endocytosis exerted impairing interacting lumen lumens morpholino morpholinos partner phosphatidylinositol shrinkage shrunken specification stereotyped studying unaffected vasculature zebrafish
Tagcloud (Intersection) ?