QTRT1 and COXFA4L2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		QTRT1	COXFA4L2
Description		queuine tRNA-ribosyltransferase catalytic subunit 1	cytochrome c oxidase hypoxia associated subunit FA4L2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Membrane Cytoplasmic Side Of Mitochondrial Outer Membrane Protein-containing Complex TRNA-guanine Transglycosylase Complex Transferase Complex	Mitochondrion Respiratory Chain Complex IV
	Molecular Function	Protein Binding TRNA-guanosine(34) Queuine Transglycosylase Activity Transferase Activity Glycosyltransferase Activity Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	TRNA Wobble Guanine Modification TRNA Modification TRNA Processing
Pathways		tRNA modification in the nucleus and cytosol
Drugs			NADH
Diseases
GWAS		Bipolar disorder ( 31043756) FEV1 ( 30804560) Inflammatory skin disease ( 25574825) Lung function (FVC) ( 30804560) Psoriasis ( 25903422)
Interacting Genes		8 interacting genes: COPS6 COXFA4L2 LCOR RHOU SETDB1 SH3GL3 UNC119 ZBTB16	14 interacting genes: ANXA9 C6orf62 COMMD8 DYNLL1 EIF3C ERG28 KAT5 KCNA4 LUC7L2 NUFIP2 PRKN QTRT1 SLC35F6 UBR1
Entrez ID		81890	56901
HPRD ID		17943	14249
Ensembl ID		ENSG00000213339	ENSG00000185633
Uniprot IDs		Q71RF8 Q9BXR0	Q9NRX3
PDB IDs		6H42 6H45 7NQ4 8OMR
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Receptor-mediated Endocytosis Transcription Corepressor Binding Negative Regulation Of Endocytosis Endocytosis Type 2 Angiotensin Receptor Binding Negative Regulation Of Caveolin-mediated Endocytosis Regulation Of Receptor-mediated Endocytosis Male Germ-line Stem Cell Asymmetric Division Germ-line Stem Cell Division Positive Regulation Of NK T Cell Differentiation Histone H3K9 Trimethyltransferase Activity Central Nervous System Development
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