ARPC5L and ARPC4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (biochemical)
HPRD (two hybrid)

		ARPC5L	ARPC4
Gene Name		actin related protein 2/3 complex, subunit 5-like	actin related protein 2/3 complex, subunit 4, 20kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Arp2/3 Protein Complex Focal Adhesion Extracellular Vesicular Exosome	Cytosol Arp2/3 Protein Complex Cell Projection Extracellular Vesicular Exosome
	Molecular Function	Molecular_function Actin Binding	Structural Constituent Of Cytoskeleton Protein Binding Enzyme Binding Protein Binding, Bridging Actin Filament Binding
	Biological Process	Biological_process Arp2/3 Complex-mediated Actin Nucleation	Axon Guidance Actin Filament Polymerization Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Actin Nucleation Innate Immune Response Ephrin Receptor Signaling Pathway
Pathways			EPHB-mediated forward signaling Axon guidance EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: ARPC4 GADD45G	10 interactors: ACTR2 ACTR3 ARPC1B ARPC2 ARPC3 ARPC5 ARPC5L NELFCD PNMA5 RNF130
Entrez ID		81873	10093
HPRD ID		12490	10368
Ensembl ID		ENSG00000136950	ENSG00000241553
Uniprot IDs		Q9BPX5	P59998
PDB IDs
Enriched GO Terms of Interacting Partners?			Arp2/3 Complex-mediated Actin Nucleation Actin Nucleation Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Actin Filament Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Regulation Of Cytoskeleton Organization Ephrin Receptor Signaling Pathway Actin Cytoskeleton Organization Actin Filament-based Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Organelle Organization Phagocytosis Fc Receptor Signaling Pathway Cytoskeleton Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Guidance Meiotic Chromosome Movement Towards Spindle Pole Immune Response-regulating Signaling Pathway Axonogenesis Axon Development Asymmetric Cell Division Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cellular Component Organization Chemotaxis Positive Regulation Of Immune Response Neuron Projection Morphogenesis Endocytosis Meiotic Cytokinesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Innate Immune Response Movement Of Cell Or Subcellular Component Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Immune Response
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