ADAMTS10 and LAMTOR3

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ADAMTS10	LAMTOR3
Gene Name		ADAM metallopeptidase with thrombospondin type 1 motif, 10	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Microfibril Extracellular Matrix	Focal Adhesion Extracellular Vesicular Exosome Ragulator Complex
	Molecular Function	Molecular_function Metalloendopeptidase Activity Protein Binding Zinc Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Complex Scaffold
	Biological Process	Proteolysis Biological_process	Positive Regulation Of TOR Signaling Cellular Protein Localization Positive Regulation Of GTPase Activity Cellular Response To Amino Acid Stimulus
Pathways		Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS		Height ( 20881960 18391951)
Protein-Protein Interactions		7 interactors: ANXA7 CDKN1A HMGCL LAMTOR3 PCYT2 SMN1 TK1	16 interactors: ADAMTS10 BHMT CEBPZ CPNE6 IBTK LAMTOR2 MAP2K1 MAP2K2 MAPK1 MAPK3 MBD2 NIF3L1 PDE4DIP QARS SUFU UBR1
Entrez ID		81794	8649
HPRD ID		07470	04485
Ensembl ID		ENSG00000142303	ENSG00000109270
Uniprot IDs		M0QZE4 Q59FE5 Q6ZN14 Q9H324	Q9UHA4
PDB IDs			1SKO 2ZL1 3CPT
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Response To Extracellular Stimulus Fetal Process Involved In Parturition Protein Tetramerization Skeletal Muscle Cell Proliferation Digestive Tract Development Digestive System Development Liver Development Response To Glucocorticoid Response To Corticosteroid Response To Toxic Substance Leucine Catabolic Process Intestinal Epithelial Cell Maturation Response To Lipid Response To Organic Cyclic Compound Response To Cortisol Thymidine Metabolic Process Cellular Response To UV-B Deoxyribonucleoside Monophosphate Biosynthetic Process Ketone Body Biosynthetic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Leucine Metabolic Process Cellular Ketone Body Metabolic Process Stress-induced Premature Senescence Response To Metal Ion Phosphatidylethanolamine Biosynthetic Process Cellular Water Homeostasis Mitotic Cell Cycle Arrest Response To UV-B Intestinal Epithelial Cell Development Anatomical Structure Development Parturition Regulation Of Protein Import Into Nucleus, Translocation Branched-chain Amino Acid Catabolic Process Intestinal Epithelial Cell Differentiation Epithelial Cell Maturation Positive Regulation Of TOR Signaling Response To Nutrient Levels Protein Oligomerization Response To Copper Ion Response To Inorganic Substance Response To Steroid Hormone Response To Arsenic-containing Substance Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Gland Development	Regulation Of Golgi Inheritance Regulation Of Golgi Organization Regulation Of Early Endosome To Late Endosome Transport Activation Of MAPKK Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Cellular Response To Organonitrogen Compound Response To Organonitrogen Compound Vascular Endothelial Growth Factor Receptor Signaling Pathway Activation Of Protein Kinase Activity Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of MAPK Activity Activation Of Innate Immune Response Insulin Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Caveolin-mediated Endocytosis Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Protein Kinase Activity Positive Regulation Of Innate Immune Response Regulation Of Stress-activated MAPK Cascade Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Intracellular Transport Regulation Of Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity Positive Regulation Of MAP Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Ras Protein Signal Transduction MAPK Cascade Neurotrophin Signaling Pathway Positive Regulation Of Kinase Activity Fc-epsilon Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Innate Immune Response
Tagcloud ?		adjuvant antitumor cdna cultured doses exert facilitate fold foundation hypericin led mcf mcf7 metastasis mfc michigan ml mug prevent purpose real separately subjected suppressive transcribed viability xtt
Tagcloud (Difference) ?		adjuvant antitumor cdna cultured doses exert facilitate fold foundation hypericin led mcf mcf7 metastasis mfc michigan ml mug prevent purpose real separately subjected suppressive transcribed viability xtt
Tagcloud (Intersection) ?