MADCAM1 and ITGB7

Number of citations of the paper that reports this interaction (PMID 9233649)
14

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		MADCAM1	ITGB7
Gene Name		mucosal vascular addressin cell adhesion molecule 1	integrin, beta 7
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integrin Complex Cell Surface Membrane Integrin Alpha4-beta7 Complex Receptor Complex Extracellular Vesicular Exosome
	Molecular Function	Integrin Binding Involved In Cell-matrix Adhesion	Virus Receptor Activity Protein Binding Metal Ion Binding Cell Adhesion Molecule Binding
	Biological Process	Positive Regulation Of Leukocyte Migration Immune Response Cell Adhesion Cell-matrix Adhesion Signal Transduction Integrin-mediated Signaling Pathway Aging Extracellular Matrix Organization Keratinocyte Differentiation Heterotypic Cell-cell Adhesion Receptor Clustering Regulation Of Immune Response Leukocyte Tethering Or Rolling	Cell-matrix Adhesion Involved In Ameboidal Cell Migration Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Multicellular Organismal Development Response To Virus Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Substrate Adhesion-dependent Cell Spreading Receptor Clustering Regulation Of Immune Response Leukocyte Tethering Or Rolling T Cell Migration
Pathways			Integrin cell surface interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		3 interactors: CD44 ITGA4 ITGB7	15 interactors: CDH1 DAB1 DOK1 EED FLNA FN1 GNB2L1 ITGA4 ITGAE MADCAM1 PRKCB PRKCD TLN1 TNS2 VCAM1
Entrez ID		8174	3695
HPRD ID		00035	00948
Ensembl ID		ENSG00000099866	ENSG00000139626
Uniprot IDs		Q13477	P26010
PDB IDs		1BQS 1GSM 4HBQ 4HC1 4HCR 4HD9	2BRQ 3V4P 3V4V
Enriched GO Terms of Interacting Partners?		Cell-matrix Adhesion Involved In Ameboidal Cell Migration Cell-matrix Adhesion Cell-substrate Adhesion Leukocyte Tethering Or Rolling Leukocyte Migration T Cell Migration Heterotypic Cell-cell Adhesion Leukocyte Cell-cell Adhesion Lymphocyte Migration Extracellular Matrix Organization Extracellular Structure Organization Cellular Extravasation Substrate Adhesion-dependent Cell Spreading Single Organismal Cell-cell Adhesion Receptor Clustering Cell Migration Cell Motility Integrin-mediated Signaling Pathway Cell Adhesion Locomotion Ameboidal-type Cell Migration Positive Regulation Of Monocyte Aggregation Movement Of Cell Or Subcellular Component Monocyte Aggregation Negative Regulation Of Protein Homodimerization Activity Protein Localization To Membrane Immune System Process Wound Healing Involved In Inflammatory Response Blood Coagulation Hemostasis Anatomical Structure Morphogenesis Chorio-allantoic Fusion Positive Regulation Of Heterotypic Cell-cell Adhesion Reproductive Structure Development Reproductive System Development Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Hyaluronan Catabolic Process Regulation Of Body Fluid Levels Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Wound Healing Cell Surface Receptor Signaling Pathway Regulation Of Protein Homodimerization Activity Response To Wounding Branching Involved In Prostate Gland Morphogenesis Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Developmental Process Involved In Reproduction Cell Morphogenesis Involved In Differentiation Labyrinthine Layer Morphogenesis Negative Regulation Of Signal Transduction By P53 Class Mediator	Cell Adhesion Regulation Of Body Fluid Levels Extracellular Matrix Organization Extracellular Structure Organization Leukocyte Tethering Or Rolling Cell Activation Platelet Activation Blood Coagulation Hemostasis Single Organismal Cell-cell Adhesion Cellular Extravasation Wound Healing Positive Regulation Of Cellular Protein Metabolic Process B Cell Activation Response To Wounding Cell-matrix Adhesion Positive Regulation Of Protein Metabolic Process Receptor Clustering Cell Junction Assembly Cell-substrate Adhesion Regulation Of Immune Response Leukocyte Migration Positive Regulation Of Protein Modification Process Platelet Degranulation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Chorio-allantoic Fusion Regulation Of Protein Metabolic Process Signal Transduction Regulation Of Cellular Process Anatomical Structure Morphogenesis Cellular Response To Stimulus Response To Stimulus Developmental Process Cell Differentiation Cell Morphogenesis Involved In Differentiation Integrin-mediated Signaling Pathway Protein Localization To Membrane Signaling Locomotion Cell Communication Regulation Of Immune System Process Regulation Of Cellular Protein Metabolic Process Labyrinthine Layer Morphogenesis Heterotypic Cell-cell Adhesion Lymphocyte Activation Multicellular Organismal Development Cell Migration Membrane Organization Embryonic Placenta Morphogenesis
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