FIP1L1 and PRMT2

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		FIP1L1	PRMT2
Gene Name		factor interacting with PAPOLA and CPSF1	protein arginine methyltransferase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Rb-E2F Complex
	Molecular Function	Poly(A) RNA Binding	Transcription Coactivator Activity Signal Transducer Activity Protein Binding Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Estrogen Receptor Binding Progesterone Receptor Binding Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Protein Homodimerization Activity Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Thyroid Hormone Receptor Binding Androgen Receptor Binding
	Biological Process	MRNA Processing	Protein Methylation Signal Transduction Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of NF-kappaB Transcription Factor Activity Histone Arginine Methylation Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Developmental Cell Growth Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		DNA methylation (variation) ( 23725790)
Protein-Protein Interactions		11 interactors: APP CPSF4 CSNK2A1 GOLGA2 LIG4 NAA10 PRMT2 PRMT6 SGTA WWOX ZMYND19	18 interactors: BAG6 CPSF7 DMRTB1 ESR1 ESR2 FIP1L1 HNRNPA1 HNRNPUL1 NCOA1 NCOA6 PGR PRRC2A PSMB3 RB1 RIPK2 RXRA SPAG8 THRB
Entrez ID		81608	3275
HPRD ID		09646	09060
Ensembl ID		ENSG00000145216	ENSG00000160310
Uniprot IDs		Q6UN15	B7U630 B7U631 P55345 Q5U7D4
PDB IDs			1X2P
Enriched GO Terms of Interacting Partners?		Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation Viral Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Neuron Death DNA Ligation Involved In DNA Recombination Apoptotic Process Programmed Cell Death Regulation Of Mitotic Cell Cycle Chromosome Organization Developmental Cell Growth Cell Death Death Modification By Virus Of Host MRNA Processing Histone H3-R2 Methylation Synaptic Growth At Neuromuscular Junction N-terminal Peptidyl-glutamic Acid Acetylation N-terminal Peptidyl-serine Acetylation Regulation Of Cell Cycle Process Histone Methylation Collateral Sprouting In Absence Of Injury Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Binding Cell Growth Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Apoptotic Process Protein Methylation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Lagging Strand Elongation Pro-B Cell Differentiation Regulation Of Cell Death Axon Choice Point Recognition Establishment Of Integrated Proviral Latency Negative Regulation Of Mitotic Cell Cycle Neuron Remodeling Immunoglobulin V(D)J Recombination Establishment Of Viral Latency T Cell Receptor V(D)J Recombination DNA Ligation Involved In DNA Repair Regulation Of RNA Metabolic Process Steroid Metabolic Process Cell Development N-terminal Protein Amino Acid Acetylation Lymphoid Progenitor Cell Differentiation Regulation Of Binding	Intracellular Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Gene Expression Transcription Initiation From RNA Polymerase II Promoter Steroid Hormone Mediated Signaling Pathway RNA Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway Transcription, DNA-templated Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Cellular Nitrogen Compound Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Lipid Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Steroid Hormone Multicellular Organismal Reproductive Process Reproductive Structure Development Reproductive System Development Multicellular Organism Reproduction Heterocycle Metabolic Process Response To Lipid Cellular Aromatic Compound Metabolic Process Ovulation Cycle Regulation Of Gene Expression Response To Organic Cyclic Compound Reproductive Process Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Response To Hormone Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Reproduction Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Developmental Process Involved In Reproduction Single Organism Reproductive Process Cellular Metabolic Process
Tagcloud ?		adenopathy always atopic cd3 cd4 chart concern contrary corticosteroids cs dermatologic eosinophil eosinophilic french hes hypereosinophilia hypereosinophilic manifestations multicentric neurologic pdgfra phenotyping rearrangement rheumatologic scarce sparing superficial tcrgammadelta yr	bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt1 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized
Tagcloud (Difference) ?		adenopathy always atopic cd3 cd4 chart concern contrary corticosteroids cs dermatologic eosinophil eosinophilic french hes hypereosinophilia hypereosinophilic manifestations multicentric neurologic pdgfra phenotyping rearrangement rheumatologic scarce sparing superficial tcrgammadelta yr	bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt1 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized
Tagcloud (Intersection) ?