CDK2AP1 and CCDC136

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CDK2AP1	CCDC136
Gene Name		cyclin-dependent kinase 2 associated protein 1	coiled-coil domain containing 136
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Perinuclear Region Of Cytoplasm	Mitochondrion Integral Component Of Membrane
	Molecular Function	DNA Polymerase Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation DNA-dependent DNA Replication Cell Cycle
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CCDC136 CDK2 CDK2AP2 MRFAP1L1 POLA1 ZNF420	62 interactors: ABT1 AQP1 ASB7 ATP5O ATXN1 BARD1 BLOC1S6 BYSL C19orf66 C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZSCAN26
Entrez ID		8099	64753
HPRD ID		03726	10887
Ensembl ID		ENSG00000111328	ENSG00000128596
Uniprot IDs		O14519	Q96JN2
PDB IDs		2KW6
Enriched GO Terms of Interacting Partners?		G1/S Transition Of Mitotic Cell Cycle Leading Strand Elongation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Replication Positive Regulation Of DNA-dependent DNA Replication Initiation Lagging Strand Elongation Regulation Of DNA-dependent DNA Replication Initiation DNA Replication, Synthesis Of RNA Primer Cellular Response To Nitric Oxide DNA Repair Positive Regulation Of DNA-dependent DNA Replication Response To Nitric Oxide Mitotic Cell Cycle Process Telomere Maintenance Via Semi-conservative Replication Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Gene Silencing Double-strand Break Repair Via Nonhomologous End Joining Nuclear DNA Replication Telomere Maintenance Via Recombination Cellular Response To Reactive Nitrogen Species Mitotic Cell Cycle Cellular Macromolecule Biosynthetic Process Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Cellular Response To DNA Damage Stimulus DNA Strand Elongation Macromolecule Biosynthetic Process Telomere Maintenance Via Telomere Lengthening DNA Replication Initiation Centrosome Duplication Histone Phosphorylation Chromosome Organization Cell Cycle Process DNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Centrosome Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Nucleobase-containing Compound Metabolic Process Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of DNA Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process	Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process Chromatin Organization Chromatin Modification Cellular Metabolic Process Organelle Organization Cell Cycle Regulation Of Cellular Process Chromosome Organization Negative Regulation Of Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Chromatin Remodeling Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Protein Sumoylation Regulation Of Cell Cycle Signal Transduction In Response To DNA Damage Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Catabolic Process Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process Regulation Of Protein Metabolic Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host 'de Novo' Actin Filament Nucleation Transepithelial Water Transport Cardiac Muscle Thin Filament Assembly
Tagcloud ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Difference) ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Intersection) ?