CDK2AP1 and CDK2AP2

Number of citations of the paper that reports this interaction (PMID 14985111)
6

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, two hybrid, in vitro)

		CDK2AP1	CDK2AP2
Gene Name		cyclin-dependent kinase 2 associated protein 1	cyclin-dependent kinase 2 associated protein 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Polymerase Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation DNA-dependent DNA Replication Cell Cycle
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CCDC136 CDK2 CDK2AP2 MRFAP1L1 POLA1 ZNF420	17 interactors: A2M APP CDK2AP1 DBN1 EED EEF1G HSF4 IKZF1 MBTPS1 MRFAP1L1 PYCR1 RCC1 RPLP1 TRA2A WARS YIF1A ZBTB48
Entrez ID		8099	10263
HPRD ID		03726	13242
Ensembl ID		ENSG00000111328	ENSG00000167797
Uniprot IDs		O14519	O75956 Q6IAV4
PDB IDs		2KW6	2M1L
Enriched GO Terms of Interacting Partners?		G1/S Transition Of Mitotic Cell Cycle Leading Strand Elongation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Replication Positive Regulation Of DNA-dependent DNA Replication Initiation Lagging Strand Elongation Regulation Of DNA-dependent DNA Replication Initiation DNA Replication, Synthesis Of RNA Primer Cellular Response To Nitric Oxide DNA Repair Positive Regulation Of DNA-dependent DNA Replication Response To Nitric Oxide Mitotic Cell Cycle Process Telomere Maintenance Via Semi-conservative Replication Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Gene Silencing Double-strand Break Repair Via Nonhomologous End Joining Nuclear DNA Replication Telomere Maintenance Via Recombination Cellular Response To Reactive Nitrogen Species Mitotic Cell Cycle Cellular Macromolecule Biosynthetic Process Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Cellular Response To DNA Damage Stimulus DNA Strand Elongation Macromolecule Biosynthetic Process Telomere Maintenance Via Telomere Lengthening DNA Replication Initiation Centrosome Duplication Histone Phosphorylation Chromosome Organization Cell Cycle Process DNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Centrosome Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Nucleobase-containing Compound Metabolic Process Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of DNA Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process	Gene Expression Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Nuclease Activity Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Platelet Degranulation Cellular Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Macromolecule Biosynthetic Process Tryptophanyl-tRNA Aminoacylation Synaptic Growth At Neuromuscular Junction Negative Regulation Of Complement Activation, Lectin Pathway Cellular Aromatic Compound Metabolic Process Biosynthetic Process Endoplasmic Reticulum Unfolded Protein Response Cellular Metabolic Process Regulation Of Protein Metabolic Process Collateral Sprouting In Absence Of Injury Cell Communication By Chemical Coupling Regulation Of Multicellular Organism Growth Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Positive Regulation Of Protein Modification Process Cholesterol Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition L-proline Biosynthetic Process Sterol Metabolic Process Response To Unfolded Protein Cellular Protein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Hydrolase Activity Protein Metabolic Process Axon Choice Point Recognition Positive Regulation Of NK T Cell Differentiation Regulation Of Protein Phosphorylation MRNA Metabolic Process Histone H3-K9 Demethylation Response To Endoplasmic Reticulum Stress Positive Regulation Of Ran GTPase Activity Positive Regulation Of Granulocyte Differentiation
Tagcloud ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Difference) ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
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