CYB5B and SLC71A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYB5B	SLC71A2
Description		cytochrome b5 type B	solute carrier family 71 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Membrane Intracellular Membrane-bounded Organelle Nitric-oxide Synthase Complex	Membrane
	Molecular Function	Protein Binding Heme Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity	Protein Binding Transmembrane Transporter Activity
	Biological Process	Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Response To Oxidative Stress	Transmembrane Transport
Pathways		Sphingolipid de novo biosynthesis eNOS activation Phase I - Functionalization of compounds
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 29403010 30993211)
Interacting Genes		51 interacting genes: AHNAK2 APP AQP6 BIK BNIP3L BTNL9 CD33 CD79A CGRRF1 CLDN7 CLN8 CPLX4 CREB3 EBP ERGIC3 FAM209A FAM210B FKBP7 FNDC9 FRMD3 GJB5 GPR152 IGSF9 KCNK5 KIR2DL3 LMNA MARCHF8 MFF MUC1 NDUFAF2 PDZK1IP1 PHACTR3 PLPP4 REEP4 RETREG3 SDHAF4 SLC10A1 SLC10A6 SLC16A2 SLC35H1 SLC39A9 SLC60A2 SLC71A2 STOM STX1A SYT1 TMEM139 TMEM237 TMEM35A TMEM41A TMEM86B	75 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ARLN ATP13A1 BNIP3 C14orf180 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1
Entrez ID		80777	84641
HPRD ID		13106	07869
Ensembl ID		ENSG00000103018	ENSG00000148110
Uniprot IDs		O43169	Q5SR56
PDB IDs		3NER
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Endomembrane System Membrane Organization Organelle Membrane Fusion Vesicle Fusion Membrane Fusion Golgi Trans Cisterna Golgi Medial Cisterna Vesicle-mediated Transport Lysophosphatidic Acid Acyltransferase Activity Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane SNAP Receptor Activity Organelle Fusion SNARE Complex Golgi Apparatus 1-acylglycerol-3-phosphate O-acyltransferase Activity Cellular Localization Golgi Membrane Trans-Golgi Network Establishment Of Protein Localization To Membrane Secretion By Cell Protein Binding Establishment Of Protein Localization Lipid Biosynthetic Process Acyltransferase Activity
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