CYB5B and FKBP7

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		CYB5B	FKBP7
Description		cytochrome b5 type B	FKBP prolyl isomerase 7
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Membrane Intracellular Membrane-bounded Organelle Nitric-oxide Synthase Complex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding Heme Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding Isomerase Activity Metal Ion Binding
	Biological Process	Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Response To Oxidative Stress
Pathways		Sphingolipid de novo biosynthesis eNOS activation Phase I - Functionalization of compounds
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 29403010 30993211)	Alanine aminotransferase levels ( 33547301) Appendicular lean mass ( 33097823) Aspartate aminotransferase levels ( 33547301) Atrial fibrillation ( 30061737) Blood protein levels ( 30072576) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		51 interacting genes: AHNAK2 APP AQP6 BIK BNIP3L BTNL9 CD33 CD79A CGRRF1 CLDN7 CLN8 CPLX4 CREB3 EBP ERGIC3 FAM209A FAM210B FKBP7 FNDC9 FRMD3 GJB5 GPR152 IGSF9 KCNK5 KIR2DL3 LMNA MARCHF8 MFF MUC1 NDUFAF2 PDZK1IP1 PHACTR3 PLPP4 REEP4 RETREG3 SDHAF4 SLC10A1 SLC10A6 SLC16A2 SLC35H1 SLC39A9 SLC60A2 SLC71A2 STOM STX1A SYT1 TMEM139 TMEM237 TMEM35A TMEM41A TMEM86B	107 interacting genes: ABHD16A ADGRE2 ADIPOQ AP1M1 APOD ASPH BET1 BMP10 BRICD5 C3orf52 CD81 CDIPT CDS2 CERCAM CFTR CIAO2A CLCA4 CLDN19 CNIH1 CTSA CXCL16 CYB561D2 CYB5B DIABLO ERMP1 FAM3C FARS2 GET3 H4C7 HHATL HMOX1 HSBP1L1 HTATIP2 IER3 IFITM3 IGFBP5 IRF2 JOSD2 LAT LNPEP MAN2B2 MIEF2 MRM1 NFU1 NKG7 NPFFR2 OCIAD1 OXNAD1 PBX3 PCYT1A PEX16 PEX19 PLLP PLP1 PLP2 PLPP6 PPIF PRMT6 PTCD1 PTPN9 RBFA RPRM RUSF1 SELENOK SERP1 SGTA SLC30A3 SLC38A7 SLC7A14 SNX1 SNX12 STATH STX7 STX8 SUCLA2 TARS2 TCP11X2 TECR TF THAP4 THSD7B TMEM108 TMEM120B TMEM147 TMEM14A TMEM229B TMEM239 TMEM54 TMEM86A TMEM86B TMEM97 TRAM1L1 TSPAN2 TSPO2 TTPA TXNDC12 UBIAD1 UBQLN4 UNC93B1 UPK1B UPK2 VSTM4 WFDC2 WIPI2 YIPF4 YIPF6 ZFPL1
Entrez ID		80777	51661
HPRD ID		13106	08451
Ensembl ID		ENSG00000103018	ENSG00000079150
Uniprot IDs		O43169	B4DRE2 Q9Y680
PDB IDs		3NER
Enriched GO Terms of Interacting Partners?		Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein Binding Chloride Channel Inhibitor Activity Regulation Of Cellular Localization Cellular Localization Protein Insertion Into ER Membrane Transferrin Receptor Binding Alkenylglycerophosphocholine Hydrolase Activity Lysosome Peroxisome Membrane Biogenesis Intraciliary Transport Particle B Binding Cholesterol Binding Establishment Of Localization In Cell
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