SLC71A2 and DEFB127

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC71A2	DEFB127
Description		solute carrier family 71 member 2	defensin beta 127
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Extracellular Region
	Molecular Function	Protein Binding Transmembrane Transporter Activity	Protein Binding
	Biological Process	Transmembrane Transport	Defense Response Defense Response To Bacterium Innate Immune Response Defense Response To Gram-negative Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways			Beta defensins Defensins
Drugs
Diseases
GWAS			Coronary artery disease in type 1 diabetes ( 32077919)
Interacting Genes		75 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ARLN ATP13A1 BNIP3 C14orf180 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1	14 interacting genes: AQP6 ASZ1 AURKAIP1 BCL2L13 CD79A CPLX4 EBP FAM174A FCER1G LMNA MMGT1 PIANP SLC71A2 TFEC
Entrez ID		84641	140850
HPRD ID		07869	10877
Ensembl ID		ENSG00000148110	ENSG00000088782
Uniprot IDs		Q5SR56	Q9H1M4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Endomembrane System Membrane Organization Organelle Membrane Fusion Vesicle Fusion Membrane Fusion Golgi Trans Cisterna Golgi Medial Cisterna Vesicle-mediated Transport Lysophosphatidic Acid Acyltransferase Activity Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane SNAP Receptor Activity Organelle Fusion SNARE Complex Golgi Apparatus 1-acylglycerol-3-phosphate O-acyltransferase Activity Cellular Localization Golgi Membrane Trans-Golgi Network Establishment Of Protein Localization To Membrane Secretion By Cell Protein Binding Establishment Of Protein Localization Lipid Biosynthetic Process Acyltransferase Activity
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