SLC71A2 and LPCAT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC71A2	LPCAT2
Description		solute carrier family 71 member 2	lysophosphatidylcholine acyltransferase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Lipid Droplet Plasma Membrane Membrane Organelle Subcompartment
	Molecular Function	Protein Binding Transmembrane Transporter Activity	1-acylglycerol-3-phosphate O-acyltransferase Activity Calcium Ion Binding Protein Binding O-acyltransferase Activity Transferase Activity Acyltransferase Activity Lysophosphatidic Acid Acyltransferase Activity Metal Ion Binding 2-acylglycerol-3-phosphate O-acyltransferase Activity Plasmalogen Synthase Activity 1-acylglycerophosphocholine O-acyltransferase Activity 1-alkylglycerophosphocholine O-acetyltransferase Activity
	Biological Process	Transmembrane Transport	Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Platelet Activating Factor Biosynthetic Process Phospholipid Biosynthetic Process Phosphatidylcholine Acyl-chain Remodeling Membrane Organization
Pathways			Acyl chain remodelling of PC
Drugs
Diseases
GWAS			Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Thyroid hormone levels ( 23408906)
Interacting Genes		75 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ARLN ATP13A1 BNIP3 C14orf180 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1	8 interacting genes: CREB3 EBP ERGIC3 HSD17B13 KCNJ6 RETREG3 RHBDD1 SLC71A2
Entrez ID		84641	54947
HPRD ID		07869	07913
Ensembl ID		ENSG00000148110	ENSG00000087253
Uniprot IDs		Q5SR56	Q7L5N7
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Endomembrane System Membrane Organization Organelle Membrane Fusion Vesicle Fusion Membrane Fusion Golgi Trans Cisterna Golgi Medial Cisterna Vesicle-mediated Transport Lysophosphatidic Acid Acyltransferase Activity Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane SNAP Receptor Activity Organelle Fusion SNARE Complex Golgi Apparatus 1-acylglycerol-3-phosphate O-acyltransferase Activity Cellular Localization Golgi Membrane Trans-Golgi Network Establishment Of Protein Localization To Membrane Secretion By Cell Protein Binding Establishment Of Protein Localization Lipid Biosynthetic Process Acyltransferase Activity	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Response To Unfolded Protein Positive Regulation Of Deacetylase Activity C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Cholestenol Delta-isomerase Activity Retrograde Transporter Complex, Golgi To ER Membrane Protein Proteolysis Involved In Retrograde Protein Transport, ER To Cytosol Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol Steroid Delta-isomerase Activity Steroid Dehydrogenase Activity G-protein Activated Inward Rectifier Potassium Channel Activity Transporter Complex Endoplasmic Reticulum-autophagosome Adaptor Activity Release From Viral Latency Regulation Of Male Germ Cell Proliferation CCR1 Chemokine Receptor Binding Regulation Of Germ Cell Proliferation
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