CUL5 and SOX30

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CUL5	SOX30
Gene Name		cullin 5	SRY (sex determining region Y)-box 30
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Cul5-RING Ubiquitin Ligase Complex	Nucleus
	Molecular Function	Receptor Activity Calcium Channel Activity Protein Binding Ubiquitin Protein Ligase Binding Protein Heterodimerization Activity	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process Response To Osmotic Stress Cell Cycle Arrest Cell Proliferation Negative Regulation Of Cell Proliferation Viral Process Protein Ubiquitination Cytosolic Calcium Ion Homeostasis Calcium Ion Transmembrane Transport Intrinsic Apoptotic Signaling Pathway	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Spermatogenesis Response To Corticosteroid
Pathways		Signaling by ERBB2 Vif-mediated degradation of APOBEC3G Antigen processing: Ubiquitination & Proteasome degradation HIV Infection Host Interactions of HIV factors Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: ANAPC11 ARIH2 ASB11 CBFB CCNDBP1 COMMD1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS8 DCUN1D3 DCUN1D4 DCUN1D5 GOLGA2 GPS1 NEDD8 PRKACA PTPN5 RBX1 RHOBTB1 RHOBTB2 RNF7 SMAD2 SMURF1 SOX30 TCEB1 TCEB2 TGFBR1 UBE2F VHL	16 interactors: AHCYL1 BAMBI BRCA1 C6orf165 CUL5 DCAF4 DDX56 FBXO38 FLI1 GNAI3 GP2 KIFC3 NME1 NUDT3 PAXIP1 TRAF2
Entrez ID		8065	11063
HPRD ID		03444	09461
Ensembl ID		ENSG00000166266	ENSG00000039600
Uniprot IDs		Q93034	B4DXW7 O94993
PDB IDs		3DPL 3DQV 4JGH
Enriched GO Terms of Interacting Partners?		Cullin Deneddylation Protein Deneddylation Cellular Protein Modification Process Protein Modification By Small Protein Removal Cellular Protein Metabolic Process Protein Neddylation Protein Modification By Small Protein Conjugation Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Catabolic Process Cellular Response To Oxygen Levels Regulation Of Transcription From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Cellular Macromolecule Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Proteolysis Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Binding Positive Regulation Of Cellular Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Cholesterol Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Response To Abiotic Stimulus Intracellular Signal Transduction Response To Hypoxia Activin Receptor Signaling Pathway Inactivation Of MAPK Activity Cellular Response To Growth Factor Stimulus Regulation Of Protein Binding Positive Regulation Of Cellular Biosynthetic Process Response To Growth Factor Positive Regulation Of Dense Core Granule Biogenesis Protein Polyubiquitination Positive Regulation Of Viral Transcription Peptidyl-threonine Phosphorylation Negative Regulation Of Cell Proliferation	Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Binding Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Positive Regulation Of Histone Methylation Protein Ubiquitination Protein Autoubiquitination Regulation Of Histone Acetylation Protein Modification By Small Protein Conjugation Regulation Of Histone Methylation Regulation Of Binding Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Antigen Transcytosis By M Cells In Mucosal-associated Lymphoid Tissue Positive Regulation Of Histone H4-K16 Acetylation Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Positive Regulation Of Protein Binding Positive Regulation Of Histone Modification DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Histone H3-K9 Acetylation Signal Transduction In Response To DNA Damage Cellular Response To Tumor Necrosis Factor Zonula Adherens Maintenance Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Response To Tumor Necrosis Factor Positive Regulation Of Protein Ubiquitination S-adenosylmethionine Cycle Cellular Response To Indole-3-methanol Response To Ionizing Radiation Regulation Of Protein Binding Positive Regulation Of DNA Metabolic Process Negative Regulation Of Centriole Replication Positive Regulation Of Adaptive Immune Response Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of Glial Cell Apoptotic Process Protein Polyubiquitination Protein K6-linked Ubiquitination Chorion Development Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Intrinsic Apoptotic Signaling Pathway Nucleobase-containing Small Molecule Metabolic Process
Tagcloud ?		293te7 accumulated adenovirus cul2 cytoplasm deleted e1 e1b55k e3 e4orf6 efficiently export exported fastidiousness hadv heterotypic homotypic illustrate indispensable interacted interacts late ligase mre11 mrnas reason ubiquitin versa vice	activating advance antitumorigenic attenuates blockade box cactttg doi ectopic harboring hypermethylated hypermethylation indeed lung methylated onc oncogene online peri preferentially publication represses silence silenced sry tumoral unexplored unmethylated
Tagcloud (Difference) ?		293te7 accumulated adenovirus cul2 cytoplasm deleted e1 e1b55k e3 e4orf6 efficiently export exported fastidiousness hadv heterotypic homotypic illustrate indispensable interacted interacts late ligase mre11 mrnas reason ubiquitin versa vice	activating advance antitumorigenic attenuates blockade box cactttg doi ectopic harboring hypermethylated hypermethylation indeed lung methylated onc oncogene online peri preferentially publication represses silence silenced sry tumoral unexplored unmethylated
Tagcloud (Intersection) ?