REEP4 and MS4A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		REEP4	MS4A1
Description		receptor accessory protein 4	membrane spanning 4-domains A1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Microtubule Cytoplasmic Microtubule Membrane Endoplasmic Reticulum Tubular Network	Extracellular Space Nucleoplasm Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Plasma Membrane Raft Extracellular Exosome
	Molecular Function	Protein Binding Microtubule Binding	Epidermal Growth Factor Receptor Binding Protein Binding Immunoglobulin Binding MHC Class II Protein Complex Binding Identical Protein Binding
	Biological Process	Nuclear Envelope Organization Mitotic Nuclear Membrane Reassembly Cell Division Endoplasmic Reticulum Tubular Network Organization	Store-operated Calcium Entry Humoral Immune Response Cell Surface Receptor Signaling Pathway Response To Bacterium B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway Protein Tetramerization Calcium Ion Import Into Cytosol Positive Regulation Of Calcium Ion Import Across Plasma Membrane
Pathways
Drugs			Rituximab Ibritumomab tiuxetan Tositumomab Ofatumumab Obinutuzumab Technetium Tc-99m nofetumomab merpentan Ublituximab Ocrelizumab Mosunetuzumab Odronextamab
Diseases
GWAS		Frailty index ( 34431594) Hypertriglyceridemia ( 23505323)	Recurrent major depressive disorder ( 29317602)
Interacting Genes		101 interacting genes: AGPAT4 ARLN BCL2L1 BET1 BIK BMP10 C14orf180 C1S C2CD2L CCL4L2 CLDND2 CMTM3 COMT CTSA CYB5B CYB5R3 CYP4F2 DCBLD2 DERL1 DGAT2L6 DNAJC30 ERG28 FAM241B FBXO7 FMO1 FUNDC2 GIMAP1 GYPB HSD3B7 HTATIP2 IFITM3 ITGAM LEMD1 LEMD3 LEPROTL1 LNPEP MAL2 MOSPD3 MS4A1 NCK2 NINJ2 ORMDL1 PEX16 PLP2 PMP22 PRAF2 RTP2 RTP4 SEC22B SELENOK SELENOM SERF1A SERF1B SERP1 SFT2D1 SFT2D2 SFXN2 SFXN3 SLC25A46 SLC30A8 SLC7A8 SMAGP SMIM1 SQLE STATH STX3 STX5 SYNJ2BP TIMM22 TMEM120B TMEM121 TMEM128 TMEM14B TMEM167B TMEM18 TMEM19 TMEM208 TMEM229B TMEM254 TMEM42 TMEM50A TMEM51 TMEM60 TMEM65 TMEM86A TMX2 TPRG1 TSNARE1 TSPAN2 TVP23B UBE2J1 UBIAD1 UNC50 VAMP1 VAMP4 VAPB VMA12 VTI1B YIF1A YIPF4 YIPF6	41 interacting genes: ACKR2 AQP6 CD40 CERS4 CLEC14A CREB3 CREB3L1 CSNK2A1 CSNK2A2 FAM209A FCRL3 FYN GORAB GPR42 HSD17B11 HSD17B13 IL7R KASH5 LCK LEUTX LMNA LYN MDM2 MMD MTIF3 REEP2 REEP4 RNF19B RNF5 SLC10A1 SLC10A6 SLC18A1 SLC35H1 SLC71A2 THAP4 TMEM31 TMEM72 TMEM82 TMPPE TMX2 TSPO2
Entrez ID		80346	931
HPRD ID		09864	00204
Ensembl ID		ENSG00000168476	ENSG00000156738
Uniprot IDs		E5RGS2 Q9H6H4	P11836
PDB IDs			2OSL 3BKY 3PP4 6VJA 6Y90 6Y92 6Y97 6Y9A 8VGN 8VGO
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Endomembrane System SNAP Receptor Activity SNARE Complex Protein Binding Establishment Of Protein Localization Organelle Fusion Vesicle Fusion Organelle Membrane Fusion Mitochondrial Outer Membrane Membrane Fusion Membrane Organization Vesicle Fusion With Golgi Apparatus Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Membrane Docking Protein Transport Presynaptic Endosome Membrane Golgi Vesicle Transport Monoatomic Ion Transmembrane Transporter Activity Intracellular Transport Cellular Localization Mitochondrial Membrane Nitric-oxide Synthase Complex Vesicle Organization Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Serine Import Into Mitochondrion Olfactory Receptor Binding Establishment Of Localization In Cell Myelination Axon Ensheathment Nitrite Reductase (NO-forming) Activity Transport Vesicle Golgi Membrane Vesicle Docking Menaquinone Metabolic Process SNARE Binding Golgi Organization Import Into The Mitochondrion Bcl-2 Family Protein Complex Mitochondrial Transport	Membrane Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Protein Kinase CK2 Complex Steroid Dehydrogenase Activity CD8 Receptor Binding Bile Acid:sodium Symporter Activity Fc-gamma Receptor Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Lymphocyte Activation Lymphocyte Proliferation Mononuclear Cell Proliferation B Cell Proliferation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway T Cell Costimulation CD4 Receptor Binding Non-membrane Spanning Protein Tyrosine Kinase Activity Endoplasmic Reticulum Endoplasmic Reticulum Membrane Peptidyl-tyrosine Phosphorylation Monocarboxylic Acid Transport Phospholipase Activator Activity Negative Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Cell Activation Fc Receptor Signaling Pathway Leukocyte Proliferation T Cell Receptor Binding Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of B Cell Proliferation Organic Hydroxy Compound Transport Protein Binding Response To Xenobiotic Stimulus Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Adaptive Immune Response Phosphatidylinositol 3-kinase Binding Negative Regulation Of Apoptotic Process Transmembrane Transport Protein Kinase Activity Negative Regulation Of Programmed Cell Death Stimulatory C-type Lectin Receptor Signaling Pathway Phospholipase Binding Cellular Response To Lectin Bile Acid And Bile Salt Transport Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Lymphocyte Activation Nuclear Envelope Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?