REEP4 and VMA12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		REEP4	VMA12
Description		receptor accessory protein 4	vacuolar ATPase assembly factor VMA12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Microtubule Cytoplasmic Microtubule Membrane Endoplasmic Reticulum Tubular Network	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Membrane Vacuolar Proton-transporting V-type ATPase Complex COPI-coated Vesicle Membrane Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Oxysterol Binding
	Biological Process	Nuclear Envelope Organization Mitotic Nuclear Membrane Reassembly Cell Division Endoplasmic Reticulum Tubular Network Organization	Intracellular Iron Ion Homeostasis Lysosomal Lumen Acidification Cellular Response To Increased Oxygen Levels Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Frailty index ( 34431594) Hypertriglyceridemia ( 23505323)
Interacting Genes		101 interacting genes: AGPAT4 ARLN BCL2L1 BET1 BIK BMP10 C14orf180 C1S C2CD2L CCL4L2 CLDND2 CMTM3 COMT CTSA CYB5B CYB5R3 CYP4F2 DCBLD2 DERL1 DGAT2L6 DNAJC30 ERG28 FAM241B FBXO7 FMO1 FUNDC2 GIMAP1 GYPB HSD3B7 HTATIP2 IFITM3 ITGAM LEMD1 LEMD3 LEPROTL1 LNPEP MAL2 MOSPD3 MS4A1 NCK2 NINJ2 ORMDL1 PEX16 PLP2 PMP22 PRAF2 RTP2 RTP4 SEC22B SELENOK SELENOM SERF1A SERF1B SERP1 SFT2D1 SFT2D2 SFXN2 SFXN3 SLC25A46 SLC30A8 SLC7A8 SMAGP SMIM1 SQLE STATH STX3 STX5 SYNJ2BP TIMM22 TMEM120B TMEM121 TMEM128 TMEM14B TMEM167B TMEM18 TMEM19 TMEM208 TMEM229B TMEM254 TMEM42 TMEM50A TMEM51 TMEM60 TMEM65 TMEM86A TMX2 TPRG1 TSNARE1 TSPAN2 TVP23B UBE2J1 UBIAD1 UNC50 VAMP1 VAMP4 VAPB VMA12 VTI1B YIF1A YIPF4 YIPF6	17 interacting genes: AQP6 BIK CCR2 CD300A EBP ELOVL4 ERLIN1 IFNGR2 JAGN1 KASH5 LMNA REEP4 SLC10A4 STX1A STX4 TIMMDC1 TMEM14B
Entrez ID		80346	147007
HPRD ID		09864	12679
Ensembl ID		ENSG00000168476	ENSG00000244045
Uniprot IDs		E5RGS2 Q9H6H4	Q8N511
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Endomembrane System SNAP Receptor Activity SNARE Complex Protein Binding Establishment Of Protein Localization Organelle Fusion Vesicle Fusion Organelle Membrane Fusion Mitochondrial Outer Membrane Membrane Fusion Membrane Organization Vesicle Fusion With Golgi Apparatus Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Membrane Docking Protein Transport Presynaptic Endosome Membrane Golgi Vesicle Transport Monoatomic Ion Transmembrane Transporter Activity Intracellular Transport Cellular Localization Mitochondrial Membrane Nitric-oxide Synthase Complex Vesicle Organization Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Serine Import Into Mitochondrion Olfactory Receptor Binding Establishment Of Localization In Cell Myelination Axon Ensheathment Nitrite Reductase (NO-forming) Activity Transport Vesicle Golgi Membrane Vesicle Docking Menaquinone Metabolic Process SNARE Binding Golgi Organization Import Into The Mitochondrion Bcl-2 Family Protein Complex Mitochondrial Transport	Membrane Regulation Of Regulated Secretory Pathway Regulation Of Exocytosis Positive Regulation Of Glutamate Receptor Signaling Pathway Regulation Of Glutamate Receptor Signaling Pathway SNARE Complex Assembly Regulation Of Secretion By Cell Nuclear Envelope Organization Regulation Of Secretion Endoplasmic Reticulum Membrane Positive Regulation Of Synaptic Transmission Nitrate Transmembrane Transporter Activity Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrial Membrane Organelle Localization SNARE Complex Regulation Of Insulin Secretion Insulin Secretion Positive Regulation Of Regulated Secretory Pathway Regulation Of Peptide Hormone Secretion SNAP Receptor Activity Myosin Head/neck Binding Exocytosis Sphingomyelin Phosphodiesterase Activator Activity Cholesterol-5,6-oxide Hydrolase Activity Negative Regulation Of Secretion Negative Regulation Of Secretion By Cell Negative Regulation Of Eosinophil Activation Negative Regulation Of Exocytosis Negative Regulation Of Phagocytosis, Engulfment Negative Regulation Of Eosinophil Degranulation Positive Regulation Of Astrocyte Chemotaxis T-helper 17 Cell Chemotaxis Chemokine (C-C Motif) Ligand 12 Binding Chemokine (C-C Motif) Ligand 2 Binding Nuclear Envelope PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Type II Interferon Receptor Activity DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina SNARE Binding Vesicle Docking Regulation Of Vesicle-mediated Transport Positive Regulation Of Eosinophil Degranulation Membrane Assembly Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Storage Vacuole C-8 Sterol Isomerase Activity Cholestenol Delta-isomerase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?