VMA12 and SLC10A4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VMA12	SLC10A4
Description		vacuolar ATPase assembly factor VMA12	solute carrier family 10 member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Membrane Vacuolar Proton-transporting V-type ATPase Complex COPI-coated Vesicle Membrane Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding Oxysterol Binding	Protein Binding Bile Acid:sodium Symporter Activity Symporter Activity
	Biological Process	Intracellular Iron Ion Homeostasis Lysosomal Lumen Acidification Cellular Response To Increased Oxygen Levels Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process	Monoatomic Ion Transport Sodium Ion Transport Bile Acid And Bile Salt Transport Transmembrane Transport
Pathways
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Crohn's disease ( 23128233)
Interacting Genes		17 interacting genes: AQP6 BIK CCR2 CD300A EBP ELOVL4 ERLIN1 IFNGR2 JAGN1 KASH5 LMNA REEP4 SLC10A4 STX1A STX4 TIMMDC1 TMEM14B	5 interacting genes: COL4A5 DNAJC30 SLC35A4 TMEM218 VMA12
Entrez ID		147007	201780
HPRD ID		12679	11562
Ensembl ID		ENSG00000244045	ENSG00000145248
Uniprot IDs		Q8N511	Q96EP9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Regulation Of Regulated Secretory Pathway Regulation Of Exocytosis Positive Regulation Of Glutamate Receptor Signaling Pathway Regulation Of Glutamate Receptor Signaling Pathway SNARE Complex Assembly Regulation Of Secretion By Cell Nuclear Envelope Organization Regulation Of Secretion Endoplasmic Reticulum Membrane Positive Regulation Of Synaptic Transmission Nitrate Transmembrane Transporter Activity Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrial Membrane Organelle Localization SNARE Complex Regulation Of Insulin Secretion Insulin Secretion Positive Regulation Of Regulated Secretory Pathway Regulation Of Peptide Hormone Secretion SNAP Receptor Activity Myosin Head/neck Binding Exocytosis Sphingomyelin Phosphodiesterase Activator Activity Cholesterol-5,6-oxide Hydrolase Activity Negative Regulation Of Secretion Negative Regulation Of Secretion By Cell Negative Regulation Of Eosinophil Activation Negative Regulation Of Exocytosis Negative Regulation Of Phagocytosis, Engulfment Negative Regulation Of Eosinophil Degranulation Positive Regulation Of Astrocyte Chemotaxis T-helper 17 Cell Chemotaxis Chemokine (C-C Motif) Ligand 12 Binding Chemokine (C-C Motif) Ligand 2 Binding Nuclear Envelope PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Type II Interferon Receptor Activity DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina SNARE Binding Vesicle Docking Regulation Of Vesicle-mediated Transport Positive Regulation Of Eosinophil Degranulation Membrane Assembly Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Storage Vacuole C-8 Sterol Isomerase Activity Cholestenol Delta-isomerase Activity	Collagen-activated Signaling Pathway Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Collagen Type IV Trimer Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport Nucleotide-sugar Transmembrane Transport Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity Pyrimidine Nucleotide-sugar Transmembrane Transport COPI-coated Vesicle Membrane Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process Proton-transporting V-type ATPase Complex Assembly Oxysterol Binding Vacuolar Proton-transporting V-type ATPase Complex Cellular Response To Increased Oxygen Levels Protein Catabolic Process In The Vacuole Regulation Of ATP Biosynthetic Process
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