MIIP and TCHP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MIIP	TCHP
Description		migration and invasion inhibitory protein	trichoplein keratin filament binding
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Mitochondrion Centrosome Cytosol Cytoskeleton Plasma Membrane Cilium Membrane Desmosome Nuclear Membrane Ciliary Basal Body Keratin Filament Apical Cortex Anchoring Junction Polymeric Cytoskeletal Fiber
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Migration	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851) Serum alkaline phosphatase levels ( 33339817) Tuberculosis ( 29036319)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Myocardial infarction ( 30226566) Platelet count ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		25 interacting genes: BCAS2 CCDC120 CYSRT1 EFHC1 EIF3E FRS3 ITGB3 KCTD9 KPRP KRT34 MED28 MOB2 OIP5 OTX1 PPP1CA STK16 TCHP TEKT4 TLE5 TRIM55 TRIM63 TRIP6 USHBP1 ZDHHC17 ZNF417	52 interacting genes: ATPAF2 BCAS2 C21orf91 CBY2 CCDC125 CCDC13 CCDC172 CCDC85B CDR2 CDR2L DMAP1 DYDC1 EIF4ENIF1 HOOK2 ID2 IFFO1 IKZF3 KCTD17 KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT32 KRT34 KRT35 KRT40 KRT5 KRT6A KRT75 KRT8 MIIP MIPOL1 MKRN3 MTUS2 NAB2 NDOR1 NME7 NUP54 PRDM16 PSMB5 RABGEF1 RUSC1 TEX11 TRIM27 TRIM54 USHBP1 VIM WWOX ZIM2
Entrez ID		60672	84260
HPRD ID		07768	14403
Ensembl ID		ENSG00000116691	ENSG00000139437
Uniprot IDs		Q5JXC2	Q9BT92
PDB IDs
Enriched GO Terms of Interacting Partners?			Intermediate Filament Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Structural Molecule Activity Cytoskeleton Organization Cytoskeleton Structural Constituent Of Cytoskeleton Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Cell Differentiation Cellular Developmental Process Organelle Organization Protein Binding Scaffold Protein Binding Epidermis Development Cytosol Keratinization Keratin Filament Binding Cell Periphery Developmental Process Anatomical Structure Morphogenesis Intermediate Filament Cytoskeleton Nuclear Matrix Cornified Envelope Hair Cycle Centrosome Hepatocyte Apoptotic Process
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