CCDC6 and SNAPC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC6	SNAPC1
Description		coiled-coil domain containing 6	small nuclear RNA activating complex polypeptide 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton	Nucleus Nucleoplasm Nucleolus SnRNA-activating Protein Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding SH3 Domain Binding Identical Protein Binding	RNA Polymerase III General Transcription Initiation Factor Activity DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Sequence-specific DNA Binding
	Biological Process	Cytoskeleton Organization	SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases		Thyroid cancer
GWAS		Alopecia areata ( 25608926) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Chronotype ( 30696823) Metabolite levels ( 23823483)
Interacting Genes		31 interacting genes: ATF2 ATF5 CCDC136 CCDC33 CREB1 CSNK2A1 CYTH4 DRC4 DSCR9 FBXW7 LHX3 LRSAM1 LUZP4 MAPK3 MAPK7 MEOX2 PAX6 PIN1 PPP4C SH3RF1 SNAPC1 SORBS3 TFIP11 TRIM14 UBE2I WAC ZNF250 ZNF354C ZNF620 ZNF774 ZNF835	14 interacting genes: CCDC6 EXOC8 HAT1 HOXA10 HSF2BP NR2E3 RB1 RHOXF2 SAAL1 SNAPC3 SNAPC4 SNAPC5 TBP TRIM29
Entrez ID		8030	6617
HPRD ID		09064	08998
Ensembl ID		ENSG00000108091	ENSG00000023608
Uniprot IDs		Q05CP8 Q16204	B2RC42 Q16533
PDB IDs			7XUR 7ZWC 7ZWD 7ZX7 7ZX8 7ZXE 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Nucleus Phosphothreonine Residue Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of DNA-templated Transcription Regulation Of Ubiquitin-dependent Protein Catabolic Process Pituitary Gland Development Regulation Of Macromolecule Biosynthetic Process Regulation Of Macroautophagy Positive Regulation Of Macroautophagy Regulation Of Proteasomal Protein Catabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Catabolic Process MAPK Cascade Transcription Coregulator Binding Protein Stabilization Positive Regulation Of Xenophagy Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Gland Development Negative Regulation Of Proteolysis Signal Transduction In Response To DNA Damage DNA Binding CAMP Response Element Binding Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Autophagy MAP Kinase Activity Positive Regulation Of Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA Damage Response Positive Regulation Of Catabolic Process Positive Regulation Of Macromolecule Metabolic Process	RNA Polymerase III General Transcription Initiation Factor Activity Transcription By RNA Polymerase III SnRNA Transcription By RNA Polymerase III Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase II SnRNA Transcription DNA-templated Transcription SnRNA-activating Protein Complex RNA Polymerase II General Transcription Initiation Factor Activity SnRNA Metabolic Process RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Nucleobase-containing Compound Biosynthetic Process Core Promoter Sequence-specific DNA Binding Nucleoplasm Male Gamete Generation Spermatogenesis RNA Metabolic Process Macromolecule Biosynthetic Process DNA Binding Gamete Generation RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Regulator Complex Chromatin Bent DNA Binding DNA-templated Transcription Initiation Chromatin Lock Complex Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Lipid Kinase Activity Positive Regulation Of Collagen Fibril Organization TFIIB-class Transcription Factor Binding Positive Regulation Of Synoviocyte Proliferation Nucleic Acid Metabolic Process
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