CCDC6 and CCDC33

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC6	CCDC33
Description		coiled-coil domain containing 6	coiled-coil domain containing 33
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton	Peroxisome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding SH3 Domain Binding Identical Protein Binding	Protein Binding
	Biological Process	Cytoskeleton Organization
Pathways
Drugs
Diseases		Thyroid cancer
GWAS		Alopecia areata ( 25608926) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Bacterial meningitis ( 31092817) Coffee consumption (cups per day) ( 31837886) Craniofacial microsomia ( 26853712) Diastolic blood pressure ( 30224653) Diisocyanate-induced asthma ( 25918132) Hip circumference adjusted for BMI ( 34021172) Obesity-related traits ( 23251661) Systolic blood pressure ( 30578418)
Interacting Genes		31 interacting genes: ATF2 ATF5 CCDC136 CCDC33 CREB1 CSNK2A1 CYTH4 DRC4 DSCR9 FBXW7 LHX3 LRSAM1 LUZP4 MAPK3 MAPK7 MEOX2 PAX6 PIN1 PPP4C SH3RF1 SNAPC1 SORBS3 TFIP11 TRIM14 UBE2I WAC ZNF250 ZNF354C ZNF620 ZNF774 ZNF835	159 interacting genes: ABCF3 ABLIM3 AIRIM ANKS1A AP1M1 APP ARHGEF6 ARIH2 ARMC7 ARNT2 ATOSB BCCIP BLK BLZF1 BYSL CABP2 CALCOCO2 CCDC102B CCDC57 CCDC6 CCDC85B CCHCR1 CCNH CDC23 CDCA7L CDKN2B CENPP CFAP206 CHCHD3 CINP CIRSR CRYBA2 CRYBA4 CTNNA3 DGCR6 DIP2A DVL2 DVL3 EAF1 EFEMP2 EHMT2 EMC2 EMD ESRRG EXOC8 FAM124A FAM161A FRS3 FXR2 GCC1 GPANK1 GPATCH2L GRN GYS1 HEXIM2 HGS HNRNPF HNRNPK HOOK2 HOXA1 HSF2BP IL16 ING5 ITGB1BP1 KANK2 KCTD19 KCTD9 KDM1A KHDRBS3 KIFC3 KLHL38 KXD1 L3MBTL2 LDOC1 LMO1 LMO2 LMO3 LNX1 MAGED1 MAGOHB MAPK9 MDFI MFAP1 MID2 MIPOL1 MISP MKRN3 MLH1 MOS NAB2 NCK2 NDOR1 NECAB2 NEFL NINL NME7 OSGIN1 OSTF1 PCSK5 PID1 PIK3R3 PIN1 PLA2G6 PLSCR1 PNMA1 PNMA2 POLR1C PPP2R3C PRKAA2 PRKAB2 PRPF31 PTGER3 PTK6 QARS1 RAD51D RAD54B RBMX RHOXF2 RNF6 SCNM1 SMAD3 SMARCB1 SMARCD1 SMYD1 SPAG5 SPG21 STK16 STX11 SYT17 TASOR2 TCEANC TGFB1 TMCC2 TNS2 TRAF2 TRIM23 TRIM37 TRIM42 TRIM59 TSC22D4 TSEN15 TSGA10 TTC19 TUFT1 TXK TXLNA UBASH3A UBQLN4 USHBP1 VPS52 WT1 YES1 ZBTB8A ZGPAT ZNF330 ZNF572 ZNF688 ZNF76 ZNRD2
Entrez ID		8030	80125
HPRD ID		09064	09959
Ensembl ID		ENSG00000108091	ENSG00000140481
Uniprot IDs		Q05CP8 Q16204	A0A1B0GV97 Q8N5R6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Nucleus Phosphothreonine Residue Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of DNA-templated Transcription Regulation Of Ubiquitin-dependent Protein Catabolic Process Pituitary Gland Development Regulation Of Macromolecule Biosynthetic Process Regulation Of Macroautophagy Positive Regulation Of Macroautophagy Regulation Of Proteasomal Protein Catabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Catabolic Process MAPK Cascade Transcription Coregulator Binding Protein Stabilization Positive Regulation Of Xenophagy Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Gland Development Negative Regulation Of Proteolysis Signal Transduction In Response To DNA Damage DNA Binding CAMP Response Element Binding Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Autophagy MAP Kinase Activity Positive Regulation Of Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA Damage Response Positive Regulation Of Catabolic Process Positive Regulation Of Macromolecule Metabolic Process	Protein Binding Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleoplasm Cytoplasm Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Macromolecule Biosynthetic Process CD4 Receptor Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Neuron Maturation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Speck Spliceosomal Complex Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Enzyme Binding
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