PHAF1 and NPBWR2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		PHAF1	NPBWR2
Name		phagophore assembly factor 1	neuropeptides B and W receptor 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Cytoplasm Trans-Golgi Network Dendrite Synaptic Vesicle Membrane	Plasma Membrane Membrane Neuron Projection
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity G Protein-coupled Opioid Receptor Activity Protein Binding Neuropeptide Receptor Activity Neuropeptide Binding
	Biological Process	Golgi To Plasma Membrane Protein Transport	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway G Protein-coupled Opioid Receptor Signaling Pathway
Pathways		None	Peptide ligand-binding receptors G alpha (i) signalling events
GWAS		No GWAS studies recorded	Body mass index ( 25673413 ) Cerebrospinal AB1-42 levels in normal cognition ( 29274321 ) Medication use (agents acting on the renin-angiotensin system) ( 31015401 )
Novel Interactors		3 novel interactors: CYB5B ESRP2 QSOX1	2 novel interactors: CHPF RRM2
Interacting Genes		10 interacting genes: APP ATXN3 CBFA2T2 CCDC102B KIF17 MPPED1 NPBWR2 PRR5L TOLLIP TSHZ2	18 interacting genes: BOLL CYSRT1 KPRP KRT31 KRT34 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 KRTAP6-2 NOTCH2NLA NPB NPW PHAF1 PNMA1 PSMA3
Entrez ID		80262	2832
HPRD ID		17460	02841
Ensembl ID		ENSG00000125149	ENSG00000125522
Uniprot IDs		Q9BSU1	P48146
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Intermediate Filament Keratin Filament Epidermis Development Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Establishment Of Skin Barrier Tissue Development Structural Molecule Activity Skin Epidermis Development