PHAF1 and MPPED1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PHAF1	MPPED1
Description		phagophore assembly factor 1	metallophosphoesterase domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Cytoplasm Trans-Golgi Network Dendrite Synaptic Vesicle Membrane	Cellular_component
	Molecular Function	Protein Binding	Molecular_function Protein Binding Hydrolase Activity
	Biological Process	Golgi To Plasma Membrane Protein Transport	Biological_process
Pathways
Drugs
Diseases
GWAS			Femur bone mineral density x serum urate levels interaction ( 34046847) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Sleep (1/2-day periodicity) ( 33075057)
Interacting Genes		10 interacting genes: APP ATXN3 CBFA2T2 CCDC102B KIF17 MPPED1 NPBWR2 PRR5L TOLLIP TSHZ2	6 interacting genes: ANXA7 DISC1 PHAF1 SPP1 TK1 ZRANB1
Entrez ID		80262	758
HPRD ID		17460	03663
Ensembl ID		ENSG00000125149	ENSG00000186732
Uniprot IDs		Q9BSU1	O15442
PDB IDs
Enriched GO Terms of Interacting Partners?			Integrin Binding Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Regulation Of Axonogenesis DNA Synthesis Involved In Mitotic DNA Replication Thymidine Kinase Activity Pyramidal Neuron Migration To Cerebral Cortex Positive Regulation Of Wnt Signaling Pathway Central Region Of Growth Cone Response To Ketone Chromaffin Granule Membrane Regulation Of Anatomical Structure Morphogenesis Androgen Catabolic Process Cellular Response To Testosterone Stimulus Response To 2,3,7,8-tetrachlorodibenzodioxine Thymidine Metabolic Process Thymidine Biosynthetic Process Radial Glia-guided Pyramidal Neuron Migration Cerebral Cortex Radial Glia-guided Migration Protein K33-linked Deubiquitination Protein K29-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Response To Macrophage Colony-stimulating Factor Deoxyribonucleoside Monophosphate Biosynthetic Process Wnt Signaling Pathway Response To Phorbol 13-acetate 12-myristate Positive Regulation Of Bone Resorption Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Negative Regulation Of Neuron Projection Regeneration Pyrimidine Nucleoside Metabolic Process
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