PHAF1 and TSHZ2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PHAF1	TSHZ2
Description		phagophore assembly factor 1	teashirt zinc finger homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Cytoplasm Trans-Golgi Network Dendrite Synaptic Vesicle Membrane	Chromatin Nucleus
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Golgi To Plasma Membrane Protein Transport	Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression
Pathways
Drugs
Diseases
GWAS			A body shape index ( 34021172) Adventurousness ( 30643258) Age at first sexual intercourse ( 34211149) Alcohol consumption (max-drinks) ( 29460428) Apolipoprotein A1 levels ( 32203549) Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Coronary artery aneurysm in Kawasaki disease ( 27171184) Crohn's disease ( 32581322) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Femur bone mineral density x serum urate levels interaction ( 34046847) General risk tolerance (MTAG) ( 30643258) Hemoglobin ( 19862010) Hip index ( 34021172) Parkinson's disease ( 26227905) Spatial memory ( 31596458) Triglyceride levels ( 32203549) Triglyceride levels x loop diuretics use interaction ( 31806883) Type 2 diabetes ( 30297969) Type 2 diabetes (age of onset) ( 28060188) Urinary metabolite levels in chronic kidney disease ( 29545352) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		10 interacting genes: APP ATXN3 CBFA2T2 CCDC102B KIF17 MPPED1 NPBWR2 PRR5L TOLLIP TSHZ2	21 interacting genes: APBB1 BACH2 CCDC57 CCDC88B CNTROB COG3 CRACR2B GIGYF1 GOLGA2 GRIPAP1 MCC PHAF1 PIBF1 PNMA1 RABEP1 RINT1 SPTA1 TFIP11 TRAF1 TRAF2 UBE2I
Entrez ID		80262	128553
HPRD ID		17460	10730
Ensembl ID		ENSG00000125149	ENSG00000182463
Uniprot IDs		Q9BSU1	Q9NRE2
PDB IDs
Enriched GO Terms of Interacting Partners?			Golgi Vesicle Transport Thioesterase Binding Microtubule Organizing Center Organization Cytoplasm Cellular Localization Microtubule Nucleation Establishment Of Protein Localization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Membraneless Organelle Assembly Tumor Necrosis Factor Receptor Binding Centriole Assembly Centriole Replication
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