LHX3 and IFT172

Number of citations of the paper that reports this interaction (PMID 10788441)
7

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		LHX3	IFT172
Gene Name		LIM homeobox 3	intraflagellar transport 172
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Cilium Axoneme Intraciliary Transport Particle B Vesicle Ciliary Basal Body Primary Cilium Sperm Midpiece Sperm Principal Piece Ciliary Tip Sperm Cytoplasmic Droplet
	Molecular Function	RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Placenta Development Transcription From RNA Polymerase II Promoter Motor Neuron Axon Guidance Organ Morphogenesis Spinal Cord Motor Neuron Cell Fate Specification Ventral Spinal Cord Interneuron Specification Medial Motor Column Neuron Differentiation Spinal Cord Association Neuron Differentiation Pituitary Gland Development Lung Development Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Inner Ear Development	Neural Tube Closure Heart Looping Organelle Organization Notch Signaling Pathway Smoothened Signaling Pathway Brain Development Epidermis Development Dorsal/ventral Pattern Formation Protein Processing Spinal Cord Motor Neuron Differentiation Cytoplasmic Microtubule Organization Cilium Assembly Positive Regulation Of Smoothened Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Palate Development Limb Development Bone Development Hindgut Development Left/right Axis Specification
Pathways			Organelle biogenesis and maintenance Hedgehog 'off' state Signaling by Hedgehog Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS		Height ( 20189936) Thyroid hormone levels ( 23408906)	Calcium levels ( 20705733) Chronic kidney disease ( 20383146) Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		8 interactors: CITED2 IFT172 ISL1 ISL2 LDB1 LHX1 LMX1A RLIM	2 interactors: LHX3 LHX4
Entrez ID		8022	26160
HPRD ID		02783	09576
Ensembl ID		ENSG00000107187	ENSG00000138002
Uniprot IDs		F1T0D5 F1T0D7 F1T0D9 Q9UBR4	B3KP68 Q9UG01
PDB IDs
Enriched GO Terms of Interacting Partners?		Central Nervous System Neuron Differentiation Ventral Spinal Cord Development Cell Differentiation In Spinal Cord Spinal Cord Development Axis Specification Central Nervous System Development Pattern Specification Process Visceral Motor Neuron Differentiation Neuron Differentiation Spinal Cord Motor Neuron Differentiation Anatomical Structure Morphogenesis Brain Development Generation Of Neurons Head Development Cell Projection Morphogenesis Neurogenesis Cell Part Morphogenesis Organ Development Axon Guidance Peripheral Nervous System Neuron Development Cerebellum Development Left/right Axis Specification Metencephalon Development Anatomical Structure Formation Involved In Morphogenesis Cell Morphogenesis Cell Differentiation Cerebellar Purkinje Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Spinal Cord Motor Neuron Cell Fate Specification Embryo Development Cell Projection Organization Cerebellar Purkinje Cell Layer Morphogenesis Axonogenesis Nervous System Development Transcription, DNA-templated Hindbrain Development Axon Development Left/right Pattern Formation Retinal Ganglion Cell Axon Guidance Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Organ Morphogenesis RNA Biosynthetic Process Negative Regulation Of Gene Expression Chemotaxis Negative Regulation Of Biosynthetic Process Negative Regulation Of Neuron Differentiation Neuron Projection Morphogenesis Cerebellar Cortex Formation	Medial Motor Column Neuron Differentiation Somatic Motor Neuron Differentiation Motor Neuron Axon Guidance Spinal Cord Motor Neuron Differentiation Ventral Spinal Cord Development Cell Differentiation In Spinal Cord Spinal Cord Development Placenta Development Central Nervous System Neuron Differentiation Axon Guidance Reproductive Structure Development Reproductive System Development Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Developmental Process Involved In Reproduction Ventral Spinal Cord Interneuron Specification Neuron Projection Development Spinal Cord Association Neuron Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Spinal Cord Motor Neuron Cell Fate Specification Ventral Spinal Cord Interneuron Fate Commitment Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Ventral Spinal Cord Interneuron Differentiation Neuron Development Central Nervous System Development Negative Regulation Of Cell Death Organ Morphogenesis Dorsal Spinal Cord Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Single Organism Reproductive Process Spinal Cord Dorsal/ventral Patterning Neuron Fate Specification Spinal Cord Patterning Locomotion Reproductive Process Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Regulation Of Cell Death Generation Of Neurons Pituitary Gland Development Neurogenesis Cell Development
Tagcloud ?		balanced binary circuit collaboration cord directing diversification enhancers excitatory expense fate gabaergic gata2 generating glutamatergic immature initiates interneuons interneuron interneurons lim lmo4 nli nucleates spinal v2 v2a v2b ventral	anchors apparatus assembled caenorhabditis centrosomal chlamydomonas cilia cilium displaces dyf elipsa flag gmap210 golgi hspb11 ift20 ift25 ift54 ift54s ift88 immunoprecipitate intraflagellar liss localize motil orthologue orthologues traf3ip1
Tagcloud (Difference) ?		balanced binary circuit collaboration cord directing diversification enhancers excitatory expense fate gabaergic gata2 generating glutamatergic immature initiates interneuons interneuron interneurons lim lmo4 nli nucleates spinal v2 v2a v2b ventral	anchors apparatus assembled caenorhabditis centrosomal chlamydomonas cilia cilium displaces dyf elipsa flag gmap210 golgi hspb11 ift20 ift25 ift54 ift54s ift88 immunoprecipitate intraflagellar liss localize motil orthologue orthologues traf3ip1
Tagcloud (Intersection) ?