THOC7 and MED18

Number of citations of the paper that reports this interaction (PMID 12584197)
12

Data Source:
BioGRID (pull down)

		THOC7	MED18
Gene Name		THO complex 7 homolog (Drosophila)	mediator complex subunit 18
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Mediator Complex
	Molecular Function	RNA Binding Protein Binding	RNA Polymerase II Transcription Cofactor Activity Protein Binding
	Biological Process	MRNA Processing MRNA Export From Nucleus RNA Splicing Viral MRNA Export From Host Cell Nucleus	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ALYREF CHD3 CKAP4 DDX39B GOT2 MED18 MED22 MED8 NIF3L1 THOC5	8 interactors: CAMK2B HOMEZ MED20 MED31 MED9 THOC7 TRIM39 USP49
Entrez ID		80145	54797
HPRD ID		17632	17476
Ensembl ID		ENSG00000163634	ENSG00000130772
Uniprot IDs		Q6I9Y2	B4DJL3 Q9BUE0
PDB IDs
Enriched GO Terms of Interacting Partners?		Viral MRNA Export From Host Cell Nucleus Intracellular Transport Of Virus Positive Regulation Of DNA-templated Transcription, Elongation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of DNA Damage Checkpoint Regulation Of DNA-templated Transcription, Elongation Cellular Nitrogen Compound Metabolic Process MRNA Export From Nucleus Nitrogen Compound Metabolic Process RNA Export From Nucleus Regulation Of DNA Damage Checkpoint Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear Export MRNA Transport Regulation Of RNA Metabolic Process RNA Transport RNA Localization RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Viral Life Cycle Regulation Of Cell Cycle Checkpoint Nucleocytoplasmic Transport Nuclear Transport Transcription From RNA Polymerase II Promoter RNA Splicing Nucleobase-containing Compound Metabolic Process Biosynthetic Process MRNA Processing Cellular Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process MRNA Metabolic Process RNA Biosynthetic Process Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of Response To DNA Damage Stimulus RNA Processing Fumarate Metabolic Process Dihydrobiopterin Metabolic Process RNA Secondary Structure Unwinding Regulation Of Stem Cell Division	RNA Metabolic Process Gene Expression Inhibitory G-protein Coupled Receptor Phosphorylation Histone H2B Conserved C-terminal Lysine Deubiquitination Activation Of Meiosis Involved In Egg Activation Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Activation Of Meiosis Cellular Aromatic Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Synaptic Transmission, Cholinergic Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Viral MRNA Export From Host Cell Nucleus Nitrogen Compound Metabolic Process Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Skeletal Muscle Adaptation Regulation Of Synapse Structural Plasticity Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Dendritic Spine Morphogenesis RNA Splicing Positive Regulation Of Synapse Maturation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Meiotic Nuclear Division Histone Deubiquitination Egg Activation Regulation Of Synapse Maturation Regulation Of Protein Catabolic Process MRNA Processing Positive Regulation Of Dendritic Spine Development Intracellular Transport Of Virus Regulation Of Cellular Response To Heat Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Dendritic Spine Morphogenesis
Tagcloud ?			aba abscisic arabidopsis associates conveys cues deregulated engender evolutionarily flowering frigida4 glutaredoxins grx480 grxs13 h5 insensitive mediator multifunctional occupancy reinforcing termination terminator thioredoxin tri trx underpinning yang1 yin yy1
Tagcloud (Difference) ?			aba abscisic arabidopsis associates conveys cues deregulated engender evolutionarily flowering frigida4 glutaredoxins grx480 grxs13 h5 insensitive mediator multifunctional occupancy reinforcing termination terminator thioredoxin tri trx underpinning yang1 yin yy1
Tagcloud (Intersection) ?