MED18

Gene Name		mediator complex subunit 18
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mediator Complex
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-protein Interactions		8 interactors: CAMK2B HOMEZ MED20 MED31 MED9 THOC7 TRIM39 USP49
Entrez ID		54797
HPRD ID		17476
Ensembl ID		ENSG00000130772
Uniprot IDs		B4DJL3 Q9BUE0
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Inhibitory G-protein Coupled Receptor Phosphorylation Histone H2B Conserved C-terminal Lysine Deubiquitination Activation Of Meiosis Involved In Egg Activation Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Activation Of Meiosis Cellular Aromatic Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Synaptic Transmission, Cholinergic Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Viral MRNA Export From Host Cell Nucleus Nitrogen Compound Metabolic Process Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Skeletal Muscle Adaptation Regulation Of Synapse Structural Plasticity Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Dendritic Spine Morphogenesis RNA Splicing Positive Regulation Of Synapse Maturation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Meiotic Nuclear Division Histone Deubiquitination Egg Activation Regulation Of Synapse Maturation Regulation Of Protein Catabolic Process MRNA Processing Positive Regulation Of Dendritic Spine Development Intracellular Transport Of Virus Regulation Of Cellular Response To Heat Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Dendritic Spine Morphogenesis
Tagcloud ?		aba abscisic arabidopsis associates conveys cues deregulated engender evolutionarily flowering frigida4 glutaredoxins grx480 grxs13 h5 insensitive mediator multifunctional occupancy reinforcing termination terminator thioredoxin tri trx underpinning yang1 yin yy1