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PTGES2 and CEBPB
Number of citations of the paper that reports this interaction (PMID
15879117
)
5
Data Source:
HPRD
(in vivo, in vitro)
PTGES2
CEBPB
Gene Name
prostaglandin E synthase 2
CCAAT/enhancer binding protein (C/EBP), beta
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Nucleus
Mitochondrion
Cytosol
Integral Component Of Membrane
Perinuclear Region Of Cytoplasm
Condensed Chromosome, Centromeric Region
Nuclear Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
Molecular Function
DNA Binding
Electron Carrier Activity
Protein Disulfide Oxidoreductase Activity
Lyase Activity
Heme Binding
Glutathione Binding
Prostaglandin-E Synthase Activity
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
DNA Binding
Chromatin Binding
Sequence-specific DNA Binding Transcription Factor Activity
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Glucocorticoid Receptor Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Biological Process
Prostaglandin Biosynthetic Process
Cell Redox Homeostasis
Positive Regulation Of Transcription, DNA-templated
Secretion
Oxidation-reduction Process
Embryonic Placenta Development
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Acute-phase Response
Inflammatory Response
Immune Response
Neuron Differentiation
Response To Lipopolysaccharide
Mammary Gland Epithelial Cell Proliferation
Response To Endoplasmic Reticulum Stress
Negative Regulation Of Neuron Apoptotic Process
Regulation Of Interleukin-6 Biosynthetic Process
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Brown Fat Cell Differentiation
Mammary Gland Epithelial Cell Differentiation
Regulation Of Transcription Involved In Cell Fate Commitment
Cellular Response To Amino Acid Stimulus
Pathways
Transcriptional regulation of white adipocyte differentiation
Cellular Senescence
Senescence-Associated Secretory Phenotype (SASP)
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
4 interactors:
C1orf189
CEBPB
EXOSC10
PTGFR
54 interactors:
AR
ATF2
ATF4
CAMK2A
CCL3
CEBPA
CEBPD
CEBPG
CREB1
CREBBP
DDIT3
EGFR
EGR1
ELK1
EP300
ESR1
FOXO1
HMGA1
HMGB1
HNRNPK
HOMER3
HSF1
KAT2A
KAT2B
MAPK1
MAPK3
MED23
MYB
MYC
NCOR2
NFKB1
NOLC1
NR3C1
PTGES2
RARB
RB1
RELA
RPS6KA1
RPS6KA5
RUNX1
RUNX2
SMAD3
SMAD4
SMARCA4
SMARCB1
SMARCC1
SP1
SPI1
SPIB
SRF
STAT5A
STAT6
TAF9
TRIM28
Entrez ID
80142
1051
HPRD ID
07458
01801
Ensembl ID
ENSG00000148334
ENSG00000172216
Uniprot IDs
A6NHH0
B3KPZ2
B4DWP1
Q9H7Z7
P17676
PDB IDs
1GTW
1GU4
1GU5
1H88
1H89
1H8A
1HJB
1IO4
2E42
2E43
Enriched GO Terms of Interacting Partners
?
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Cellular Response To Acid Chemical
Nuclear Polyadenylation-dependent RRNA Catabolic Process
CUT Catabolic Process
Response To Lipopolysaccharide
Response To Molecule Of Bacterial Origin
Cellular Response To Prostaglandin D Stimulus
Nuclear MRNA Surveillance
RNA Surveillance
Histone MRNA Catabolic Process
Dosage Compensation By Inactivation Of X Chromosome
Response To Bacterium
Intracellular MRNA Localization
Dosage Compensation
RRNA Catabolic Process
Calcium-mediated Signaling Using Intracellular Calcium Source
Maturation Of 5.8S RRNA
Parturition
Cellular Response To Prostaglandin Stimulus
Histone MRNA Metabolic Process
Response To Other Organism
Regulation Of Interleukin-6 Biosynthetic Process
Mammary Gland Epithelial Cell Proliferation
Mammary Gland Epithelial Cell Differentiation
Regulation Of Transcription Involved In Cell Fate Commitment
Response To Biotic Stimulus
Response To Lipid
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Acute-phase Response
Negative Regulation Of Cell Death
Brown Fat Cell Differentiation
Cellular Response To Fatty Acid
Positive Regulation Of Fat Cell Differentiation
Cellular Response To Amino Acid Stimulus
Reproductive Process
Response To Fatty Acid
Positive Regulation Of Osteoblast Differentiation
Acute Inflammatory Response
Regulation Of Apoptotic Process
Epithelial Cell Proliferation
Calcium-mediated Signaling
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Regulation Of Cell Death
Positive Regulation Of Ossification
Mammary Gland Epithelium Development
Regulation Of Interleukin-6 Production
RNA Phosphodiester Bond Hydrolysis
Regulation Of Cytokine Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Response To Organic Substance
Regulation Of Metabolic Process
Nitrogen Compound Metabolic Process
Response To Organic Substance
Negative Regulation Of RNA Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
DNA-templated Transcription, Initiation
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Immune System Process
Cellular Metabolic Process
System Development
Developmental Process
Gland Development
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Multicellular Organismal Development
Cellular Response To Stimulus
Negative Regulation Of Cellular Metabolic Process
Anatomical Structure Development
Organ Development
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Growth Factor Stimulus
Tagcloud
?
activates
anticancer
atf4
attenuated
autophagy
chip
ddit4
depletion
effectively
elusive
exo
genomic
greatly
largely
mitochondria
mtorc1
nude
pad
pan
perturbation
potentials
remain
resolution
responsive
sesn2
triple
unveiled
xenograft
yw3
Tagcloud (Difference)
?
activates
anticancer
atf4
attenuated
autophagy
chip
ddit4
depletion
effectively
elusive
exo
genomic
greatly
largely
mitochondria
mtorc1
nude
pad
pan
perturbation
potentials
remain
resolution
responsive
sesn2
triple
unveiled
xenograft
yw3
Tagcloud (Intersection)
?