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PTGES2 and PTGFR
Number of citations of the paper that reports this interaction (PMID
8300593
)
31
Data Source:
HPRD
(in vivo)
PTGES2
PTGFR
Gene Name
prostaglandin E synthase 2
prostaglandin F receptor (FP)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Nucleus
Mitochondrion
Cytosol
Integral Component Of Membrane
Perinuclear Region Of Cytoplasm
Extracellular Region
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Molecular Function
DNA Binding
Electron Carrier Activity
Protein Disulfide Oxidoreductase Activity
Lyase Activity
Heme Binding
Glutathione Binding
Prostaglandin-E Synthase Activity
Prostaglandin F Receptor Activity
Biological Process
Prostaglandin Biosynthetic Process
Cell Redox Homeostasis
Positive Regulation Of Transcription, DNA-templated
Secretion
Oxidation-reduction Process
G-protein Coupled Receptor Signaling Pathway
Parturition
Positive Regulation Of Cell Proliferation
Response To Lipopolysaccharide
Calcium-mediated Signaling Using Intracellular Calcium Source
Negative Regulation Of Apoptotic Process
Cellular Response To Prostaglandin D Stimulus
Pathways
G alpha (q) signalling events
G alpha (q) signalling events
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
Prostanoid ligand receptors
GPCR downstream signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Class A/1 (Rhodopsin-like receptors)
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Eicosanoid ligand-binding receptors
Drugs
Travoprost
Latanoprost
Bimatoprost
Dinoprost Tromethamine
Tafluprost
Diseases
GWAS
Bipolar disorder (
22182935
)
Protein-Protein Interactions
4 interactors:
C1orf189
CEBPB
EXOSC10
PTGFR
4 interactors:
PTGDS
PTGER1
PTGER2
PTGES2
Entrez ID
80142
5737
HPRD ID
07458
08988
Ensembl ID
ENSG00000148334
ENSG00000122420
Uniprot IDs
A6NHH0
B3KPZ2
B4DWP1
Q9H7Z7
P43088
PDB IDs
Enriched GO Terms of Interacting Partners
?
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Cellular Response To Acid Chemical
Nuclear Polyadenylation-dependent RRNA Catabolic Process
CUT Catabolic Process
Response To Lipopolysaccharide
Response To Molecule Of Bacterial Origin
Cellular Response To Prostaglandin D Stimulus
Nuclear MRNA Surveillance
RNA Surveillance
Histone MRNA Catabolic Process
Dosage Compensation By Inactivation Of X Chromosome
Response To Bacterium
Intracellular MRNA Localization
Dosage Compensation
RRNA Catabolic Process
Calcium-mediated Signaling Using Intracellular Calcium Source
Maturation Of 5.8S RRNA
Parturition
Cellular Response To Prostaglandin Stimulus
Histone MRNA Metabolic Process
Response To Other Organism
Regulation Of Interleukin-6 Biosynthetic Process
Mammary Gland Epithelial Cell Proliferation
Mammary Gland Epithelial Cell Differentiation
Regulation Of Transcription Involved In Cell Fate Commitment
Response To Biotic Stimulus
Response To Lipid
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Acute-phase Response
Negative Regulation Of Cell Death
Brown Fat Cell Differentiation
Cellular Response To Fatty Acid
Positive Regulation Of Fat Cell Differentiation
Cellular Response To Amino Acid Stimulus
Reproductive Process
Response To Fatty Acid
Positive Regulation Of Osteoblast Differentiation
Acute Inflammatory Response
Regulation Of Apoptotic Process
Epithelial Cell Proliferation
Calcium-mediated Signaling
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Regulation Of Cell Death
Positive Regulation Of Ossification
Mammary Gland Epithelium Development
Regulation Of Interleukin-6 Production
RNA Phosphodiester Bond Hydrolysis
Regulation Of Cytokine Biosynthetic Process
Prostaglandin Biosynthetic Process
Prostaglandin Metabolic Process
Icosanoid Biosynthetic Process
Unsaturated Fatty Acid Biosynthetic Process
Icosanoid Metabolic Process
Unsaturated Fatty Acid Metabolic Process
Negative Regulation Of Eosinophil Extravasation
Response To Lipid
Fatty Acid Biosynthetic Process
Negative Regulation Of Integrin Activation
Negative Regulation Of Eosinophil Migration
Response To Lipopolysaccharide
Fatty Acid Metabolic Process
Response To Molecule Of Bacterial Origin
Regulation Of Integrin Activation
Cellular Response To Prostaglandin E Stimulus
Response To Bacterium
Cyclooxygenase Pathway
Regulation Of Circadian Sleep/wake Cycle, Sleep
ERK1 And ERK2 Cascade
Response To Prostaglandin E
Cellular Response To Prostaglandin Stimulus
Lipid Biosynthetic Process
Monocarboxylic Acid Metabolic Process
Negative Regulation Of Leukocyte Migration
Response To Organic Substance
T-helper Cell Differentiation
Response To Other Organism
Response To Biotic Stimulus
Negative Regulation Of Cytokine Secretion
CD4-positive, Alpha-beta T Cell Differentiation
CD4-positive, Alpha-beta T Cell Activation
Cellular Response To Fatty Acid
Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway
Response To Hormone
Cellular Lipid Metabolic Process
Alpha-beta T Cell Differentiation
Carboxylic Acid Metabolic Process
Regulation Of Stress Fiber Assembly
Arachidonic Acid Metabolic Process
Alpha-beta T Cell Activation
T Cell Activation Involved In Immune Response
Response To Fatty Acid
Cellular Response To Mechanical Stimulus
Organic Acid Metabolic Process
G-protein Coupled Receptor Signaling Pathway
JNK Cascade
Positive Regulation Of Cytokine Secretion
Lipid Metabolic Process
Positive Regulation Of Inflammatory Response
Tagcloud
?
11beta
9alpha
abcc4
akr1b1
akr1c1
akr1c3
catalyze
diseased
endometriosis
endometriotic
endometrium
gynecological
hieec
hiesc
hpgd
hpgds
infertility
peritoneal
pgd2
pgf2alpha
pgh2
pla2g2a
pla2g4a
provokes
ptgds
ptgs2
reaches
slco2a
synthases
Tagcloud (Difference)
?
11beta
9alpha
abcc4
akr1b1
akr1c1
akr1c3
catalyze
diseased
endometriosis
endometriotic
endometrium
gynecological
hieec
hiesc
hpgd
hpgds
infertility
peritoneal
pgd2
pgf2alpha
pgh2
pla2g2a
pla2g4a
provokes
ptgds
ptgs2
reaches
slco2a
synthases
Tagcloud (Intersection)
?