AK5 and NUCKS1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		AK5	NUCKS1
Gene Name		adenylate kinase 5	nuclear casein kinase and cyclin-dependent kinase substrate 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Cytosol	Nucleus Cytoplasm
	Molecular Function	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding Nucleoside Kinase Activity	Poly(A) RNA Binding
	Biological Process	Nucleoside Diphosphate Phosphorylation ADP Biosynthetic Process DADP Biosynthetic Process Nucleoside Triphosphate Biosynthetic Process Pyrimidine Ribonucleotide Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Small Molecule Metabolic Process ATP Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS			Parkinson's disease ( 19915575 19915576) Prostate-specific antigen levels ( 23269536) Pubertal anthropometrics ( 23449627)
Protein-Protein Interactions		7 interactors: C7orf26 CPNE6 NUCKS1 RNF114 STRN4 TRIM46 UGDH	2 interactors: AK5 GLP1R
Entrez ID		26289	64710
HPRD ID		10472	11406
Ensembl ID		ENSG00000154027	ENSG00000069275
Uniprot IDs		Q9Y6K8	B4DTY3 Q9H1E3
PDB IDs		2BWJ
Enriched GO Terms of Interacting Partners?		UDP-glucuronate Biosynthetic Process UDP-glucuronate Metabolic Process	DADP Biosynthetic Process ADP Biosynthetic Process Deoxyribonucleoside Diphosphate Metabolic Process Nucleoside Diphosphate Biosynthetic Process ADP Metabolic Process Deoxyribonucleotide Biosynthetic Process Nucleobase-containing Small Molecule Interconversion CAMP-mediated Signaling Activation Of Adenylate Cyclase Activity Cyclic-nucleotide-mediated Signaling Positive Regulation Of Adenylate Cyclase Activity Cellular Response To Glucagon Stimulus Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Positive Regulation Of Lyase Activity Deoxyribonucleotide Metabolic Process Response To Glucagon Pyrimidine Nucleotide Biosynthetic Process Regulation Of Adenylate Cyclase Activity Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Pyrimidine Nucleotide Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Regulation Of CAMP Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process Regulation Of CAMP Metabolic Process Nucleoside Monophosphate Biosynthetic Process Small Molecule Metabolic Process ATP Metabolic Process Energy Reserve Metabolic Process Second-messenger-mediated Signaling Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Heart Contraction Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Cytosolic Calcium Ion Homeostasis Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion Purine Nucleoside Metabolic Process Regulation Of Hormone Secretion Learning Or Memory Cognition Cellular Calcium Ion Homeostasis Ribonucleotide Metabolic Process Nucleoside Metabolic Process
Tagcloud ?			association associations carcinoma casein clinicopathological cytokeratin distant epidermal estrogen grade grading histological histopathological immunohistochemical invasive involvement ki lymph markers metastases node pr progesterone regard special substrate subtype ubiquitous
Tagcloud (Difference) ?			association associations carcinoma casein clinicopathological cytokeratin distant epidermal estrogen grade grading histological histopathological immunohistochemical invasive involvement ki lymph markers metastases node pr progesterone regard special substrate subtype ubiquitous
Tagcloud (Intersection) ?