TRARG1 and DAGLA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRARG1	DAGLA
Description		trafficking regulator of GLUT4 (SLC2A4) 1 (gene/pseudogene)	diacylglycerol lipase alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Membrane Cytoplasmic Vesicle Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Endosome Plasma Membrane Membrane Early Endosome Membrane Dendrite Membrane Dendritic Spine Membrane Cell Projection Varicosity Synapse Postsynaptic Membrane Postsynaptic Density Membrane
	Molecular Function		Lipoprotein Lipase Activity Protein Binding Hydrolase Activity Metal Ion Binding Monoacylglycerol Lipase Activity
	Biological Process	Cellular Response To Insulin Stimulus Glucose Import In Response To Insulin Stimulus Establishment Of Localization In Cell Protein Localization To Plasma Membrane Vesicle Fusion To Plasma Membrane Endosome To Plasma Membrane Protein Transport	Lipid Metabolic Process Acylglycerol Metabolic Process Monoacylglycerol Biosynthetic Process Neuroblast Proliferation Lipid Catabolic Process Arachidonate Metabolic Process Neurogenesis Diacylglycerol Catabolic Process Retrograde Trans-synaptic Signaling By Endocannabinoid Regulation Of Neuroinflammatory Response Cannabinoid Biosynthetic Process
Pathways			Arachidonate production from DAG
Drugs
Diseases
GWAS			Bipolar disorder ( 28115744 31043756) Fasting plasma glucose ( 32902719) Immune reponse to smallpox (secreted IL-2) ( 22610502) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Refractive error ( 32231278)
Interacting Genes		102 interacting genes: APH1A APH1B AQP12B AQP2 ARL13B BCL2L13 BIK BSCL2 C6orf89 CARINH CCR4 CD300E CD53 CD79A CLDN12 CLDN7 CLDN8 CLEC10A CXCR1 CXCR2 DAGLA EBP EFNA4 ELOVL4 ERGIC3 FAM209A FNDC9 FUT3 GJB3 GPR151 GPR42 GPR61 GPRC5D HSF2BP IFNGR2 IL3RA KASH5 KCNC1 KRT34 KRTAP5-9 LAPTM4B LHFPL5 LY6E MEOX2 MFF MRM1 MRPS18B MTIF3 NPFFR2 NPY2R ODF4 OPN1LW OPRM1 OR7D4 OSTC PDZK1IP1 PLEKHB2 PSCA RHBDL1 RHCG RTP4 SCN3B SDCBP SLC10A1 SLC10A6 SLC13A4 SLC14A2 SLC16A2 SLC1A5 SLC30A2 SLC34A2 SLC35F1 SLC36A1 SLC38A1 SLC38A11 SLC38A6 SLC39A1 SLC71A2 SLC7A1 SLC7A14 SLCO3A1 SPAG4 SSMEM1 SYNPR TAAR9 TM4SF18 TMC4 TMEM179B TMEM237 TMEM248 TMEM31 TMEM45A TMEM52B TMEM69 TMEM71 TMEM80 TMEM9 TMPPE TTYH2 WFS1 YIPF6 ZDHHC4	10 interacting genes: CMTM7 LHFPL5 MAL MALL MS4A13 STOM TMEM218 TRARG1 UPK1B VMA21
Entrez ID		286753	747
HPRD ID		18248	07092
Ensembl ID		ENSG00000184811	ENSG00000134780
Uniprot IDs		Q8IXB3	Q9Y4D2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Transmembrane Transport Amino Acid Transmembrane Transport Protein Binding Amino Acid Transmembrane Transporter Activity Amino Acid Transport Carboxylic Acid Transport Organic Acid Transport L-amino Acid Transport G Protein-coupled Receptor Activity Carboxylic Acid Transmembrane Transport Organic Acid Transmembrane Transport Organic Anion Transport L-alpha-amino Acid Transmembrane Transport Symporter Activity Amino Acid Import Across Plasma Membrane L-glutamine Transmembrane Transporter Activity Glutamine Transport Interleukin-8-mediated Signaling Pathway Interleukin-8 Receptor Activity Apical Plasma Membrane Monoatomic Ion Transport Basolateral Plasma Membrane Interleukin-8 Binding Sodium Ion Transport Transport Across Blood-brain Barrier Neutral L-amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity L-glutamine Import Across Plasma Membrane Bile Acid:sodium Symporter Activity Transmembrane Transporter Activity Gamma-secretase Complex G Protein-coupled Receptor Signaling Pathway Metal Ion Transport Inorganic Ion Transmembrane Transport C-X-C Chemokine Receptor Activity Notch Receptor Processing	Structural Constituent Of Myelin Sheath Membrane Membrane Raft Establishment Of Protein Localization To Membrane Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Protein Insertion Into Membrane Myelination Apical Plasma Membrane Axon Ensheathment Membrane Raft Polarization Apical Plasma Membrane Urothelial Plaque B-1a B Cell Differentiation Protein Localization To Paranode Region Of Axon B-1 B Cell Differentiation Localization Within Membrane Membrane Raft Distribution Peptidase Activator Activity Involved In Apoptotic Process Sensory Perception Of Sound TIM22 Mitochondrial Import Inner Membrane Insertion Complex Sensory Perception Of Mechanical Stimulus Mitochondrial Intermembrane Space Chaperone Complex Vacuolar Proton-transporting V-type ATPase Complex Assembly Proton-transporting V-type ATPase Complex Assembly Glucose Import In Response To Insulin Stimulus
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