TRARG1 and SLC35F1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRARG1	SLC35F1
Description		trafficking regulator of GLUT4 (SLC2A4) 1 (gene/pseudogene)	solute carrier family 35 member F1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Membrane Cytoplasmic Vesicle Membrane Perinuclear Region Of Cytoplasm	Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse
	Molecular Function		Protein Binding Transmembrane Transporter Activity
	Biological Process	Cellular Response To Insulin Stimulus Glucose Import In Response To Insulin Stimulus Establishment Of Localization In Cell Protein Localization To Plasma Membrane Vesicle Fusion To Plasma Membrane Endosome To Plasma Membrane Protein Transport	Transmembrane Transport
Pathways
Drugs
Diseases
GWAS			Atrial fibrillation ( 30061737 29892015 28416818) Cardiac structure and function ( 19584346) Diastolic blood pressure ( 27841878 28135244) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Heart rate ( 23583979) Hypertrophic cardiomyopathy ( 33495596) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Left ventricular global longitudinal strain ( 33495596) PR interval ( 32439900) QRS duration ( 27659466 30679814) QT interval ( 29213071 29874175 30679814 24952745 19587794 19305408) Resting heart rate ( 20639392) Systolic blood pressure ( 27841878) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) TPE interval (resting) ( 32386560)
Interacting Genes		102 interacting genes: APH1A APH1B AQP12B AQP2 ARL13B BCL2L13 BIK BSCL2 C6orf89 CARINH CCR4 CD300E CD53 CD79A CLDN12 CLDN7 CLDN8 CLEC10A CXCR1 CXCR2 DAGLA EBP EFNA4 ELOVL4 ERGIC3 FAM209A FNDC9 FUT3 GJB3 GPR151 GPR42 GPR61 GPRC5D HSF2BP IFNGR2 IL3RA KASH5 KCNC1 KRT34 KRTAP5-9 LAPTM4B LHFPL5 LY6E MEOX2 MFF MRM1 MRPS18B MTIF3 NPFFR2 NPY2R ODF4 OPN1LW OPRM1 OR7D4 OSTC PDZK1IP1 PLEKHB2 PSCA RHBDL1 RHCG RTP4 SCN3B SDCBP SLC10A1 SLC10A6 SLC13A4 SLC14A2 SLC16A2 SLC1A5 SLC30A2 SLC34A2 SLC35F1 SLC36A1 SLC38A1 SLC38A11 SLC38A6 SLC39A1 SLC71A2 SLC7A1 SLC7A14 SLCO3A1 SPAG4 SSMEM1 SYNPR TAAR9 TM4SF18 TMC4 TMEM179B TMEM237 TMEM248 TMEM31 TMEM45A TMEM52B TMEM69 TMEM71 TMEM80 TMEM9 TMPPE TTYH2 WFS1 YIPF6 ZDHHC4	7 interacting genes: AQP6 COMT GJA5 GJA8 SLC35H1 TMEM14B TRARG1
Entrez ID		286753	222553
HPRD ID		18248	18751
Ensembl ID		ENSG00000184811	ENSG00000196376
Uniprot IDs		Q8IXB3	Q5T1Q4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Transmembrane Transport Amino Acid Transmembrane Transport Protein Binding Amino Acid Transmembrane Transporter Activity Amino Acid Transport Carboxylic Acid Transport Organic Acid Transport L-amino Acid Transport G Protein-coupled Receptor Activity Carboxylic Acid Transmembrane Transport Organic Acid Transmembrane Transport Organic Anion Transport L-alpha-amino Acid Transmembrane Transport Symporter Activity Amino Acid Import Across Plasma Membrane L-glutamine Transmembrane Transporter Activity Glutamine Transport Interleukin-8-mediated Signaling Pathway Interleukin-8 Receptor Activity Apical Plasma Membrane Monoatomic Ion Transport Basolateral Plasma Membrane Interleukin-8 Binding Sodium Ion Transport Transport Across Blood-brain Barrier Neutral L-amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity L-glutamine Import Across Plasma Membrane Bile Acid:sodium Symporter Activity Transmembrane Transporter Activity Gamma-secretase Complex G Protein-coupled Receptor Signaling Pathway Metal Ion Transport Inorganic Ion Transmembrane Transport C-X-C Chemokine Receptor Activity Notch Receptor Processing	Transmembrane Transport Renal System Process Gap Junction Channel Activity Connexin Complex Gap Junction Nitrate Transmembrane Transporter Activity Norepinephrine Secretion Catechol O-methyltransferase Activity Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Cellular Response To Phosphate Starvation Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Foramen Ovale Closure Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling Regulation Of Bundle Of His Cell Action Potential Cell Communication By Chemical Coupling Pulmonary Valve Formation SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication Membrane Habituation Cell-cell Signaling Mastication Blood Vessel Development Renal Sodium Excretion Renal Albumin Absorption Renin Secretion Into Blood Stream Signaling Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Atrial Cardiac Muscle Cell Action Potential Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling Regulation Of Renin Secretion Into Blood Stream SA Node Cell To Atrial Cardiac Muscle Cell Communication Negative Regulation Of Glomerular Filtration Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling Regulation Of AV Node Cell Action Potential UDP-glucose Transmembrane Transport Carbon Dioxide Transmembrane Transporter Activity
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