TRARG1 and CLDN12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRARG1	CLDN12
Description		trafficking regulator of GLUT4 (SLC2A4) 1 (gene/pseudogene)	claudin 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Membrane Cytoplasmic Vesicle Membrane Perinuclear Region Of Cytoplasm	Plasma Membrane Bicellular Tight Junction Membrane Lateral Plasma Membrane Tight Junction Anchoring Junction Cell Periphery
	Molecular Function		Protein Binding Identical Protein Binding
	Biological Process	Cellular Response To Insulin Stimulus Glucose Import In Response To Insulin Stimulus Establishment Of Localization In Cell Protein Localization To Plasma Membrane Vesicle Fusion To Plasma Membrane Endosome To Plasma Membrane Protein Transport	Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Maintenance Of Blood-brain Barrier Tight Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases
GWAS
Interacting Genes		102 interacting genes: APH1A APH1B AQP12B AQP2 ARL13B BCL2L13 BIK BSCL2 C6orf89 CARINH CCR4 CD300E CD53 CD79A CLDN12 CLDN7 CLDN8 CLEC10A CXCR1 CXCR2 DAGLA EBP EFNA4 ELOVL4 ERGIC3 FAM209A FNDC9 FUT3 GJB3 GPR151 GPR42 GPR61 GPRC5D HSF2BP IFNGR2 IL3RA KASH5 KCNC1 KRT34 KRTAP5-9 LAPTM4B LHFPL5 LY6E MEOX2 MFF MRM1 MRPS18B MTIF3 NPFFR2 NPY2R ODF4 OPN1LW OPRM1 OR7D4 OSTC PDZK1IP1 PLEKHB2 PSCA RHBDL1 RHCG RTP4 SCN3B SDCBP SLC10A1 SLC10A6 SLC13A4 SLC14A2 SLC16A2 SLC1A5 SLC30A2 SLC34A2 SLC35F1 SLC36A1 SLC38A1 SLC38A11 SLC38A6 SLC39A1 SLC71A2 SLC7A1 SLC7A14 SLCO3A1 SPAG4 SSMEM1 SYNPR TAAR9 TM4SF18 TMC4 TMEM179B TMEM237 TMEM248 TMEM31 TMEM45A TMEM52B TMEM69 TMEM71 TMEM80 TMEM9 TMPPE TTYH2 WFS1 YIPF6 ZDHHC4	4 interacting genes: ECHS1 SEC13 STRN4 TRARG1
Entrez ID		286753	9069
HPRD ID		18248	13064
Ensembl ID		ENSG00000184811	ENSG00000157224
Uniprot IDs		Q8IXB3	B2R687 P56749
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Transmembrane Transport Amino Acid Transmembrane Transport Protein Binding Amino Acid Transmembrane Transporter Activity Amino Acid Transport Carboxylic Acid Transport Organic Acid Transport L-amino Acid Transport G Protein-coupled Receptor Activity Carboxylic Acid Transmembrane Transport Organic Acid Transmembrane Transport Organic Anion Transport L-alpha-amino Acid Transmembrane Transport Symporter Activity Amino Acid Import Across Plasma Membrane L-glutamine Transmembrane Transporter Activity Glutamine Transport Interleukin-8-mediated Signaling Pathway Interleukin-8 Receptor Activity Apical Plasma Membrane Monoatomic Ion Transport Basolateral Plasma Membrane Interleukin-8 Binding Sodium Ion Transport Transport Across Blood-brain Barrier Neutral L-amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity L-glutamine Import Across Plasma Membrane Bile Acid:sodium Symporter Activity Transmembrane Transporter Activity Gamma-secretase Complex G Protein-coupled Receptor Signaling Pathway Metal Ion Transport Inorganic Ion Transmembrane Transport C-X-C Chemokine Receptor Activity Notch Receptor Processing	3-hydroxypropionyl-CoA Dehydratase Activity Crotonyl-CoA Hydratase Activity Enoyl-CoA Hydratase Activity Delta(3)-delta(2)-enoyl-CoA Isomerase Activity 3-hydroxyacyl-CoA Dehydratase Activity Vesicle Organization Nuclear Pore Outer Ring COPII-coated Vesicle Budding GATOR2 Complex Armadillo Repeat Domain Binding Glucose Import In Response To Insulin Stimulus Vesicle Fusion To Plasma Membrane Branched-chain Amino Acid Catabolic Process COPII-coated Vesicle Cargo Loading COPII Vesicle Coat Regulation Of Modification Of Synaptic Structure FAR/SIN/STRIPAK Complex Regulation Of Modification Of Postsynaptic Structure Endosome To Plasma Membrane Protein Transport D-glucose Import Branched-chain Amino Acid Metabolic Process Intracellular Protein Transport Negative Regulation Of Hippo Signaling Membrane Organization Protein Exit From Endoplasmic Reticulum Vesicle Budding From Membrane Vesicle Cargo Loading Protein Phosphatase 2A Binding D-glucose Transmembrane Transport Hexose Transmembrane Transport
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