ERMP1 and GPRC5D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ERMP1	GPRC5D
Description		endoplasmic reticulum metallopeptidase 1	G protein-coupled receptor class C group 5 member D
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome
	Molecular Function	Protein Binding Peptidase Activity Metalloexopeptidase Activity Metallopeptidase Activity Hydrolase Activity Metal Ion Binding	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity
	Biological Process	Proteolysis Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474 31959851) Blond vs. brown/black hair color ( 30531825) Waist-hip ratio ( 28552196)
Interacting Genes		39 interacting genes: AQP2 AQP6 ATP1B4 BCL2L13 BSCL2 CD200R1 CLDN5 CLDN7 CLDN9 CLEC2D CREB3L1 ERVFRD-1 FAM209A FKBP7 FNDC9 GJA8 GPR42 GPRC5D HHLA2 HIBADH IER3IP1 IFNGR2 KCNN3 KLRC1 LYPD5 MR1 PDCD1LG2 PEX12 RHCG SLC13A4 SLC18A1 SLC22A23 SLC23A2 SLC7A14 SPAG4 SSMEM1 TMEM237 TMEM45A TMEM80	30 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1
Entrez ID		79956	55507
HPRD ID		17227	07604
Ensembl ID		ENSG00000099219	ENSG00000111291
Uniprot IDs		A0A8I5KNY4 A0A8I5KXJ0 E7ER77 Q6ZMD3 Q7Z2K6	Q9NZD1
PDB IDs			8YZK 9IMA
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Plasma Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Transmembrane Transporter Activity Protein Binding Renal Water Transport Bicellular Tight Junction Assembly External Side Of Plasma Membrane Ammonium Channel Activity Ammonium Transmembrane Transport Tight Junction Assembly Nuclear Inner Membrane Tight Junction Organization Amine Transport Water Channel Activity Carbon Dioxide Transport Structural Molecule Activity	Membrane
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