GPRC5D and TMEM79

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPRC5D	TMEM79
Description		G protein-coupled receptor class C group 5 member D	transmembrane protein 79
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome	Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Membrane Trans-Golgi Network Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity	Protein Binding Identical Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway	Epithelial Cell Maturation Hair Follicle Morphogenesis Cuticle Development Regulated Exocytosis Positive Regulation Of Epidermis Development Establishment Of Skin Barrier Cornification
Pathways
Drugs
Diseases
GWAS			Glycated hemoglobin levels ( 24647736 28898252 29170429) Mean corpuscular hemoglobin concentration ( 20139978)
Interacting Genes		30 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1	36 interacting genes: ABO AMIGO1 ANKRD46 APOD ARL13B BRICD5 CLEC7A COQ9 CPLX4 CYB5R3 FAM209A FNDC9 GIMAP1 GPRC5D LDLRAD1 LPAR3 PELI2 PLN PLP2 PVR RNF8 RPRM SEC22A SERP1 SFTPC SLN TEX264 TMEM100 TMEM14C TMEM254 TMEM97 TMPRSS2 TMPRSS4 TNMD TRAM1L1 ZCCHC12
Entrez ID		55507	84283
HPRD ID		07604	17481
Ensembl ID		ENSG00000111291	ENSG00000163472
Uniprot IDs		Q9NZD1	Q9BSE2
PDB IDs		8YZK 9IMA
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Endoplasmic Reticulum Endoplasmic Reticulum Membrane Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of Intracellular Transport Negative Regulation Of ATP-dependent Activity Negative Regulation Of Calcium Ion Import Positive Regulation Of Viral Entry Into Host Cell Regulation Of Relaxation Of Muscle
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