ERMP1 and SLC7A14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ERMP1	SLC7A14
Description		endoplasmic reticulum metallopeptidase 1	solute carrier family 7 member 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Nucleoplasm Lysosome Lysosomal Membrane Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding Peptidase Activity Metalloexopeptidase Activity Metallopeptidase Activity Hydrolase Activity Metal Ion Binding	Protein Binding Amino Acid Transmembrane Transporter Activity Gamma-aminobutyric Acid Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Proteolysis Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress	Amino Acid Transmembrane Transport Amino Acid Transport Gamma-aminobutyric Acid Import Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474 31959851) Blond vs. brown/black hair color ( 30531825) Waist-hip ratio ( 28552196)	Obesity (extreme) ( 30677029) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		39 interacting genes: AQP2 AQP6 ATP1B4 BCL2L13 BSCL2 CD200R1 CLDN5 CLDN7 CLDN9 CLEC2D CREB3L1 ERVFRD-1 FAM209A FKBP7 FNDC9 GJA8 GPR42 GPRC5D HHLA2 HIBADH IER3IP1 IFNGR2 KCNN3 KLRC1 LYPD5 MR1 PDCD1LG2 PEX12 RHCG SLC13A4 SLC18A1 SLC22A23 SLC23A2 SLC7A14 SPAG4 SSMEM1 TMEM237 TMEM45A TMEM80	47 interacting genes: ACSL5 ADGRE2 AGTRAP AIG1 APOL3 BET1 BNIP1 BNIP2 C1GALT1 CBLIF CCDC167 CCL4L2 CD53 CMTM5 DCBLD2 DERL1 EOGT ERMP1 FAM209A FAM20B FATE1 FCER1G FKBP7 IL10RA LINC00839 LTC4S MFF MGLL MMGT1 NINJ2 NSG1 PLPP6 PRB1 SCARF1 SCD SMCO4 TECR TMEM128 TMEM31 TRARG1 TREX1 UBIAD1 VAMP2 VKORC1 YIPF4 YIPF6 ZFPL1
Entrez ID		79956	57709
HPRD ID		17227	17222
Ensembl ID		ENSG00000099219	ENSG00000013293
Uniprot IDs		A0A8I5KNY4 A0A8I5KXJ0 E7ER77 Q6ZMD3 Q7Z2K6	Q8TBB6
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Plasma Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Transmembrane Transporter Activity Protein Binding Renal Water Transport Bicellular Tight Junction Assembly External Side Of Plasma Membrane Ammonium Channel Activity Ammonium Transmembrane Transport Tight Junction Assembly Nuclear Inner Membrane Tight Junction Organization Amine Transport Water Channel Activity Carbon Dioxide Transport Structural Molecule Activity	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organelle Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Fusion SNAP Receptor Activity Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Vesicle Fusion Vesicle Fusion With Golgi Apparatus Cobalt Ion Transport SNARE Complex Nuclear Envelope Fatty Acid Biosynthetic Process Intestinal Epithelial Cell Development Response To Oxygen-glucose Deprivation Establishment Of Protein Localization To Plasma Membrane Vitamin K Metabolic Process Endosome To Plasma Membrane Protein Transport Endomembrane System Columnar/cuboidal Epithelial Cell Development Golgi Vesicle Transport
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