ERMP1 and CLDN7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ERMP1	CLDN7
Description		endoplasmic reticulum metallopeptidase 1	claudin 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Bicellular Tight Junction Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane Anchoring Junction
	Molecular Function	Protein Binding Peptidase Activity Metalloexopeptidase Activity Metallopeptidase Activity Hydrolase Activity Metal Ion Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Proteolysis Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases
GWAS		Asthma ( 31619474 31959851) Blond vs. brown/black hair color ( 30531825) Waist-hip ratio ( 28552196)	Birth weight ( 27680694 31043758) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758)
Interacting Genes		39 interacting genes: AQP2 AQP6 ATP1B4 BCL2L13 BSCL2 CD200R1 CLDN5 CLDN7 CLDN9 CLEC2D CREB3L1 ERVFRD-1 FAM209A FKBP7 FNDC9 GJA8 GPR42 GPRC5D HHLA2 HIBADH IER3IP1 IFNGR2 KCNN3 KLRC1 LYPD5 MR1 PDCD1LG2 PEX12 RHCG SLC13A4 SLC18A1 SLC22A23 SLC23A2 SLC7A14 SPAG4 SSMEM1 TMEM237 TMEM45A TMEM80	77 interacting genes: AIG1 ANKRD46 APOD AQP2 ASGR1 BCL2L2 BET1 BMP10 C3orf52 CD53 CD72 CLN6 CMTM5 CNIH1 COL4A5 CXCL16 CXCL9 CYB561A3 CYB561D2 CYB5B CYBC1 EDDM3B EMP3 EPCAM ERG28 ERMP1 FAXDC2 FXYD6 GIMAP5 GLP1R GPR37L1 HGD IGFBP5 ITM2A JAGN1 LAT LEPROTL1 LPAR3 LSMEM2 MAL MALL MS4A13 NDUFB11 NIPAL4 NKG7 OLFM4 PGAP2 PLN RHOXF2 RPRM RTP2 SCAMP4 SCARF1 SEC22B SERTM1 SLC38A7 SLC61A1 SYNE4 TJP1 TMEM100 TMEM11 TMEM128 TMEM140 TMEM147 TMEM44 TMEM60 TMEM97 TNF TRARG1 TSPAN33 UBIAD1 UNC93B1 UPK1B UPK2 VAMP3 VAMP5 VSTM1
Entrez ID		79956	1366
HPRD ID		17227	07633
Ensembl ID		ENSG00000099219	ENSG00000181885
Uniprot IDs		A0A8I5KNY4 A0A8I5KXJ0 E7ER77 Q6ZMD3 Q7Z2K6	A0A384ME58 F5H496 O95471
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Plasma Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Transmembrane Transporter Activity Protein Binding Renal Water Transport Bicellular Tight Junction Assembly External Side Of Plasma Membrane Ammonium Channel Activity Ammonium Transmembrane Transport Tight Junction Assembly Nuclear Inner Membrane Tight Junction Organization Amine Transport Water Channel Activity Carbon Dioxide Transport Structural Molecule Activity	Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Plasma Membrane Localization Within Membrane Transmembrane Ascorbate Ferrireductase Activity
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