CALCR and RAMP1

Number of citations of the paper that reports this interaction (PubMedID 10385705)
0

Data Source:
HPRD (in vitro)

		CALCR	RAMP1
Description		calcitonin receptor	receptor activity modifying protein 1
Image
GO Annotations	Cellular Component	Acrosomal Vesicle Plasma Membrane Cilium Membrane Axon Amylin Receptor Complex 1 Amylin Receptor Complex 2 Amylin Receptor Complex 3	Plasma Membrane Cell Surface Membrane Receptor Complex CGRP Receptor Complex
	Molecular Function	Amyloid-beta Binding Calcitonin Gene-related Peptide Receptor Activity Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Calcitonin Receptor Activity Protein Binding Calcitonin Binding Calcitonin Family Receptor Activity Amylin Receptor Activity	Calcitonin Gene-related Peptide Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity Calcitonin Gene-related Peptide Binding
	Biological Process	Ossification Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Gene Expression Negative Regulation Of Ossification Osteoclast Differentiation Regulation Of MRNA Stability Positive Regulation Of Calcium-mediated Signaling Response To Glucocorticoid Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade Calcitonin Family Receptor Signaling Pathway Amylin Receptor Signaling Pathway Positive Regulation Of CAMP/PKA Signal Transduction Amylin Receptor 1 Signaling Pathway Amylin Receptor 2 Signaling Pathway Amylin Receptor 3 Signaling Pathway Response To Amyloid-beta Calcitonin Gene-related Peptide Receptor Signaling Pathway	Angiogenesis Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Transport Receptor Internalization Cellular Response To Hormone Stimulus Positive Regulation Of Protein Glycosylation Protein Localization To Plasma Membrane Amylin Receptor Signaling Pathway Amylin Receptor 1 Signaling Pathway Calcitonin Gene-related Peptide Receptor Signaling Pathway
Pathways		G alpha (s) signalling events Calcitonin-like ligand receptors	G alpha (s) signalling events Calcitonin-like ligand receptors
Drugs		Salmon calcitonin Pramlintide	Pramlintide
Diseases
GWAS		A body shape index ( 34021172) Birth weight ( 23202124) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 25673413 25760438 28448500 28892062) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Cutaneous leishmaniasis ( 32830257) Hip circumference ( 28552196 25673412) Lean body mass ( 28552196 28724990) Type 2 diabetes ( 32499647) Weight ( 28552196)	Obesity-related traits ( 23251661) Resting metabolic rate ( 28476931)
Interacting Genes		9 interacting genes: CALM1 FLNA GPRASP1 GPRASP2 MBL2 RAMP1 RAMP3 SQSTM1 THBS1	10 interacting genes: CALCA CALCR CALCRL DCLK3 IAPP MAL MS4A13 NKG7 SLC31A2 VIPR1
Entrez ID		799	10267
HPRD ID		00239	05515
Ensembl ID		ENSG00000004948	ENSG00000132329
Uniprot IDs		A0A0A0MSQ7 P30988	E9PC20 O60894
PDB IDs		5II0 5UZ7 6NIY 6PFO 6PGQ 7TYF 7TYH 7TYI 7TYL 7TYN 7TYO 7TYW 7TYX 7TYY 7TZF 8F0J 8F0K 8F2A 8F2B 9AUC	2YX8 3N7P 3N7R 3N7S 4RWG 5V6Y 6D1U 6E3Y 6UMG 6ZHO 6ZIS 7KNT 7KNU 7P0F 7P0I 7TYF 7TYW 8AX5 8AX6 8AX7 9AUC
Enriched GO Terms of Interacting Partners?		Amylin Receptor Activity Amylin Receptor Signaling Pathway Calcitonin Family Receptor Signaling Pathway Protein Activation Cascade Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Signal Transduction Vesicle-mediated Transport Protein Localization To Plasma Membrane Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Protein Localization To Cell Periphery Calcium Ion Transport Protein Sequestering Activity Cell Surface G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Communication Sperm Midpiece Sarcomere Regulation Of Action Potential Regulation Of Signaling Establishment Of Localization In Cell Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Protein Maturation Cellular Localization Protein Localization To Membrane Cell Surface Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Calcitonin Gene-related Peptide Binding Coreceptor Activity Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Receptor Internalization G Protein-coupled Receptor Binding Calcium-dependent Protein Binding Positive Regulation Of Protein Localization To Cell Periphery Positive Regulation Of Cell Communication Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Signaling Regulation Of Calcium-mediated Signaling Negative Regulation Of Nitric Oxide Mediated Signal Transduction Collagen V Binding Brown Fat Cell Proliferation Amphisome Positive Regulation Of Protein Localization To Membrane G Protein-coupled Receptor Catabolic Process CGRP Receptor Complex Amyloid-beta Binding Amylin Receptor Complex 3 Signal Transduction Endocytosis	Calcitonin Family Receptor Signaling Pathway Amylin Receptor 1 Signaling Pathway Amylin Receptor 2 Signaling Pathway Calcitonin Gene-related Peptide Receptor Signaling Pathway Amylin Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Calcitonin Receptor Activity Amylin Receptor 3 Signaling Pathway Calcitonin Gene-related Peptide Receptor Activity Negative Regulation Of Bone Resorption G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Bone Remodeling Positive Regulation Of CAMP/PKA Signal Transduction Negative Regulation Of Osteoclast Differentiation Regulation Of Bone Resorption Transmembrane Signaling Receptor Activity Regulation Of Bone Remodeling Regulation Of CAMP/PKA Signal Transduction Osteoclast Differentiation Negative Regulation Of Myeloid Leukocyte Differentiation Amylin Receptor Complex 2 Calcitonin Family Receptor Activity Positive Regulation Of Calcium-mediated Signaling Amylin Receptor Complex 1 Calcitonin Binding Regulation Of Copper Ion Transmembrane Transport Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cellular Response To Sucrose Stimulus Regulation Of Osteoclast Differentiation Receptor Internalization Regulation Of Tissue Remodeling Calcitonin Receptor Binding Amyloid-beta Binding Amylin Receptor Complex 3 G Protein-coupled Receptor Activity Adrenomedullin Binding CGRP Receptor Complex Negative Regulation Of Myeloid Cell Differentiation Regulation Of Calcium-mediated Signaling Amylin Receptor Activity Membrane Raft Polarization Vasoactive Intestinal Polypeptide Receptor Activity Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Adrenomedullin Receptor Complex Adrenomedullin Receptor Activity Hormone Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?