CCDC134 and CENPM

Data Source: HiPPIP (Novel)

		CCDC134	CENPM
Name		coiled-coil domain containing 134	centromere protein M
Structure		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Membrane	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	None
	Biological Process	Angiogenesis Placenta Development Ventricular System Development Positive Regulation Of Wnt Signaling Pathway Regulation Of Ossification Positive Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway Embryonic Hemopoiesis Regulation Of Protein Glycosylation Embryonic Liver Development	Chromosome Segregation
Pathways		None	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
GWAS		Alanine aminotransferase levels ( 33547301 ) Alzheimer's disease biomarkers ( 21123754 ) Intelligence (MTAG) ( 29326435 ) Meat-related diet ( 32066663 ) Plateletcrit ( 32888494 ) Processed meat consumption ( 32066663 ) Refractive error ( 32231278 )	Birth weight ( 23202124 ) Processed meat consumption ( 32066663 ) Refractive error ( 32231278 ) Schizophrenia ( 25056061 29483656 )
Novel Interactors		1 novel interactors: CENPM	5 novel interactors: C22orf46P CCDC134 DESI1 PHF5A SEPTIN3
Interacting Genes		4 interacting genes: PGRMC1 PTPRN TADA2A UBQLN4	2 interacting genes: CENPS H3C1
Entrez ID		79879	79019
HPRD ID		07988	12798
Ensembl ID		ENSG00000100147	ENSG00000100162
Uniprot IDs		B0QY51 B4DRL0 Q9H6E4	B1AHQ6 B1AHQ7 B1AHQ8 Q9NSP4
PDB IDs		Not available	4P0T 4WAU 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH
GO Terms Enriched among Interactors		Dense Core Granule Maturation Secretory Granule Maturation Positive Regulation Of Type B Pancreatic Cell Proliferation Chromosome SAGA-type Complex Positive Regulation Of Lipoprotein Transport Negative Regulation Of Autophagosome Maturation Nuclear Proteasome Complex Cytosolic Proteasome Complex	None