CENPM and C22orf46P

Data Source: HiPPIP (Novel)

		CENPM	C22orf46P
Name		centromere protein M	CTA-216E10.6
Structure			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol	None
GO Annotations	Biological Process	Chromosome Segregation	None
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	None
GWAS		Birth weight ( 23202124 ) Processed meat consumption ( 32066663 ) Refractive error ( 32231278 ) Schizophrenia ( 25056061 29483656 )	No GWAS studies recorded
Novel Interactors		5 novel interactors: C22orf46P CCDC134 DESI1 PHF5A SEPTIN3	1 novel interactors: CENPM
Interacting Genes		2 interacting genes: CENPS H3C1	3 interacting genes: APP KRT40 SMAD2
Entrez ID		79019	79640
HPRD ID		12798	08037
Ensembl ID		ENSG00000100162	ENSG00000293428
Uniprot IDs		B1AHQ6 B1AHQ7 B1AHQ8 Q9NSP4	Not available
PDB IDs		4P0T 4WAU 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH	Not available
GO Terms Enriched among Interactors		None	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Homomeric SMAD Protein Complex Paraxial Mesoderm Morphogenesis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Mesoderm Morphogenesis Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Pericardium Development Axon Choice Point Recognition Odontoblast Differentiation SMAD Protein Complex Trophoblast Cell Migration Heparan Sulfate Binding Signaling Receptor Activator Activity Heteromeric SMAD Protein Complex Peptidase Activator Activity Response To Growth Factor Cellular Response To Manganese Ion Determination Of Left/right Asymmetry In Lateral Mesoderm Anatomical Structure Morphogenesis Embryonic Foregut Morphogenesis