CENPM and CCDC134

		CENPM	CCDC134
Description		centromere protein M	coiled-coil domain containing 134
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Membrane
	Molecular Function		Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Chromosome Segregation	Angiogenesis Placenta Development Ventricular System Development Positive Regulation Of Wnt Signaling Pathway Regulation Of Ossification Positive Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway Embryonic Hemopoiesis Regulation Of Protein Glycosylation Embryonic Liver Development
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Birth weight ( 23202124) Processed meat consumption ( 32066663) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Alanine aminotransferase levels ( 33547301) Alzheimer's disease biomarkers ( 21123754) Intelligence (MTAG) ( 29326435) Meat-related diet ( 32066663) Plateletcrit ( 32888494) Processed meat consumption ( 32066663) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: CENPS H3C1	4 interacting genes: PGRMC1 PTPRN TADA2A UBQLN4
Entrez ID		79019	79879
HPRD ID		12798	07988
Ensembl ID		ENSG00000100162	ENSG00000100147
Uniprot IDs		B1AHQ6 B1AHQ7 B1AHQ8 Q9NSP4	B0QY51 B4DRL0 Q9H6E4
PDB IDs		4P0T 4WAU 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?			Dense Core Granule Maturation Secretory Granule Maturation Positive Regulation Of Type B Pancreatic Cell Proliferation Chromosome SAGA-type Complex Positive Regulation Of Lipoprotein Transport Negative Regulation Of Autophagosome Maturation Nuclear Proteasome Complex Cytosolic Proteasome Complex
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