CENPM and PHF5A

		CENPM	PHF5A
Description		centromere protein M	PHD finger protein 5A
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex Nuclear Matrix Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome
	Molecular Function		DNA Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Chromosome Segregation	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of DNA-templated Transcription Stem Cell Differentiation U2-type Prespliceosome Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Birth weight ( 23202124) Processed meat consumption ( 32066663) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Appendicular lean mass ( 33097823) Asthma ( 30929738 32296059) Asthma (childhood onset) ( 30929738) Chronotype ( 30696823) Experiencing mood swings ( 29500382) Feeling tense ( 29500382) Lamb consumption ( 32066663) Meat-related diet ( 32066663) Neuroticism ( 29255261) PR interval ( 32439900) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: CENPS H3C1	7 interacting genes: FOXB1 GTSE1 PRPF31 PRPF6 SUMO2 U2AF2 ZDHHC17
Entrez ID		79019	84844
HPRD ID		12798	15126
Ensembl ID		ENSG00000100162	ENSG00000100410
Uniprot IDs		B1AHQ6 B1AHQ7 B1AHQ8 Q9NSP4	Q7RTV0
PDB IDs		4P0T 4WAU 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH	5IFE 5O9Z 5SYB 5Z56 5Z57 5Z58 5ZYA 6AH0 6AHD 6EN4 6FF4 6FF7 6QX9 6Y50 6Y5Q 7ABG 7ABH 7ABI 7B0I 7B91 7B92 7B9C 7DVQ 7EVN 7EVO 7OMF 7ONB 7OPI 7Q3L 7Q4O 7Q4P 7QTT 7VPX 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 8Y7E
Enriched GO Terms of Interacting Partners?			Spliceosomal Complex RNA Splicing, Via Transesterification Reactions Protein-RNA Complex Assembly MRNA Splicing, Via Spliceosome RNA Localization Spliceosomal Tri-snRNP Complex Assembly U4/U6 X U5 Tri-snRNP Complex Ribonucleoprotein Complex Binding Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly U2-type Precatalytic Spliceosome Perforant Pathway To Dendrate Granule Cell Synapse Ribonucleoprotein Complex Localization Mammillothalamic Axonal Tract Development Cell Migration In Diencephalon Mammary Gland Lobule Development Mammillary Body Development RNA Splicing Poly-pyrimidine Tract Binding Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission U4atac SnRNP Inferior Colliculus Development Nuclear Speck MRNA Processing SnRNP Binding U4atac SnRNA Binding Axon Target Recognition Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Basolateral Protein Secretion Commitment Complex Protein-cysteine S-myristoyltransferase Activity SnoRNA Localization U2AF Complex MRNA Metabolic Process Pre-mRNA 3'-splice Site Binding Protein-cysteine S-stearoyltransferase Activity Spliceosomal Tri-snRNP Complex Cytoplasmic Vesicle Membrane U4 SnRNA Binding Floor Plate Development Hypothalamus Cell Migration RNA Binding Protein-macromolecule Adaptor Activity Regulation Of Neurotrophin TRK Receptor Signaling Pathway U4 SnRNP Thalamus Development Clathrin Adaptor Complex AP-1 Adaptor Complex Nucleoplasm
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