MICALL2 and DCDC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MICALL2	DCDC2
Description		MICAL like 2	doublecortin domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Endosome Cytoskeleton Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Actin Filament Bundle Cell Projection Neuron Projection Recycling Endosome Anchoring Junction	Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Cilium Axoneme Cell Projection Kinocilium
	Molecular Function	Protein Binding Filamin Binding Small GTPase Binding Actinin Binding Metal Ion Binding Actin Filament Binding	Protein Binding Kinesin Binding
	Biological Process	Actin Cytoskeleton Organization Actin Filament Polymerization Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Substrate Adhesion-dependent Cell Spreading Bicellular Tight Junction Assembly Endosome Membrane Tubulation Positive Regulation Of Protein Targeting To Mitochondrion	Neuron Migration Cellular Defense Response Nervous System Development Sensory Perception Of Sound Cell Projection Organization Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Smoothened Signaling Pathway Dendrite Morphogenesis Cilium Assembly Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 29403010) Creatinine levels ( 29403010) Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder ( 28416812) Glomerular filtration rate ( 29403010) Hematocrit ( 29403010) Hemoglobin ( 29403010) Red blood cell count ( 29403010) Resistance to antihypertensive treatment in hypertension ( 31545351) Restless legs syndrome ( 33239738) Serum uric acid levels ( 29403010 30993211) Zinc levels ( 26025379)	Airflow obstruction ( 22837378) Estimated glomerular filtration rate ( 31015462 31152163) General cognitive ability ( 29844566) Information processing speed ( 21130836) Uric acid levels ( 21294900)
Interacting Genes		6 interacting genes: ACTN1 ACTN2 ACTN3 ACTN4 CDR2 DCDC2	19 interacting genes: APP B3GNT5 CENPO CKS1B COMMD9 DYNC2LI1 FAM118A KRTAP5-9 KRTAP9-3 LMO3 MICALL2 MRFAP1 NIF3L1 NMU POP5 PTPRCAP SLC38A2 TOLLIP ZNF432
Entrez ID		79778	51473
HPRD ID		11364	09308
Ensembl ID		ENSG00000164877	ENSG00000146038
Uniprot IDs		Q8IY33	Q9UHG0
PDB IDs			2DNF
Enriched GO Terms of Interacting Partners?		Pseudopodium Cortical Actin Cytoskeleton Muscle Cell Development Transmembrane Transporter Binding Integrin Binding Z Disc Focal Adhesion Assembly Actin Filament Binding Cell Junction Cell-substrate Junction Organization Cell-substrate Junction Assembly Sarcomere Platelet Alpha Granule Lumen Actin Cytoskeleton Actin Filament Actin Cytoskeleton Organization Actin Binding Actin Filament-based Process Postsynaptic Actin Cytoskeleton Focal Adhesion Cell Projection Calcium Ion Binding Positive Regulation Of Ion Transmembrane Transporter Activity Cell Junction Assembly Positive Regulation Of Transporter Activity Transcription Coactivator Activity Cell Development Structural Constituent Of Muscle Cytoskeleton Organization Brush Border Cytoskeletal Protein Binding Organelle Organization Regulation Of Transmembrane Transporter Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Stress Fiber Cell Junction Organization Actin Filament Uncapping Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Cytoskeleton Positive Regulation Of Cation Transmembrane Transport Structural Constituent Of Postsynapse Titin Z Domain Binding Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Monoatomic Ion Transmembrane Transport Nucleoside Binding Positive Regulation Of Sodium:proton Antiporter Activity Platelet Morphogenesis
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