MICALL2 and CDR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MICALL2	CDR2
Description		MICAL like 2	cerebellar degeneration related protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Endosome Cytoskeleton Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Actin Filament Bundle Cell Projection Neuron Projection Recycling Endosome Anchoring Junction	Cytoplasm
	Molecular Function	Protein Binding Filamin Binding Small GTPase Binding Actinin Binding Metal Ion Binding Actin Filament Binding	Protein Binding
	Biological Process	Actin Cytoskeleton Organization Actin Filament Polymerization Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Substrate Adhesion-dependent Cell Spreading Bicellular Tight Junction Assembly Endosome Membrane Tubulation Positive Regulation Of Protein Targeting To Mitochondrion
Pathways
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 29403010) Creatinine levels ( 29403010) Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder ( 28416812) Glomerular filtration rate ( 29403010) Hematocrit ( 29403010) Hemoglobin ( 29403010) Red blood cell count ( 29403010) Resistance to antihypertensive treatment in hypertension ( 31545351) Restless legs syndrome ( 33239738) Serum uric acid levels ( 29403010 30993211) Zinc levels ( 26025379)	Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		6 interacting genes: ACTN1 ACTN2 ACTN3 ACTN4 CDR2 DCDC2	76 interacting genes: AMOTL2 ANKRD36BP1 AQP1 ARNT2 BEX2 C1orf216 C4orf46 CATSPERT CCDC120 CCDC13 CCDC146 CCDC187 CCDC87 CCHCR1 CDC20 CEP57L1 CHIC2 COX5B DRC12 DRC4 EIF4E2 ENKD1 FAM110A FAM161A FAM50B FAM90A1 FXR1 FZR1 GEM GMPPA HAUS1 HDAC4 HGS KANSL1 KIF5B KIFC3 LENG1 LIN37 MICALL2 MKKS MNS1 MORF4L2 MRPL28 NDN NTAQ1 OAZ2 PKN1 PRKAA2 PRPF18 PSMA1 RCOR3 RSPH14 RUNX1T1 SCNM1 SH2D4A SMARCD1 SMARCE1 TBC1D22B TCHP TEAD4 TEX28 TMCC2 TRIM23 TRIML2 TSC1 TSGA10IP TTC23 TTR TXLNA TXLNB UBTFL1 ZGPAT ZMAT2 ZNF250 ZNF35 ZNF417
Entrez ID		79778	1039
HPRD ID		11364	06681
Ensembl ID		ENSG00000164877	ENSG00000140743
Uniprot IDs		Q8IY33	Q01850
PDB IDs
Enriched GO Terms of Interacting Partners?		Pseudopodium Cortical Actin Cytoskeleton Muscle Cell Development Transmembrane Transporter Binding Integrin Binding Z Disc Focal Adhesion Assembly Actin Filament Binding Cell Junction Cell-substrate Junction Organization Cell-substrate Junction Assembly Sarcomere Platelet Alpha Granule Lumen Actin Cytoskeleton Actin Filament Actin Cytoskeleton Organization Actin Binding Actin Filament-based Process Postsynaptic Actin Cytoskeleton Focal Adhesion Cell Projection Calcium Ion Binding Positive Regulation Of Ion Transmembrane Transporter Activity Cell Junction Assembly Positive Regulation Of Transporter Activity Transcription Coactivator Activity Cell Development Structural Constituent Of Muscle Cytoskeleton Organization Brush Border Cytoskeletal Protein Binding Organelle Organization Regulation Of Transmembrane Transporter Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Stress Fiber Cell Junction Organization Actin Filament Uncapping Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Cytoskeleton Positive Regulation Of Cation Transmembrane Transport Structural Constituent Of Postsynapse Titin Z Domain Binding Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Monoatomic Ion Transmembrane Transport Nucleoside Binding Positive Regulation Of Sodium:proton Antiporter Activity Platelet Morphogenesis	Protein Binding Centrosome Cytoskeleton Ciliary Basal Body Microtubule Cytoskeleton Organization Microtubule-based Process Motile Cilium Cytoplasm Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Microtubule Binding Cilium Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Cytoskeleton Organization Cell Projection Cilium Organization Polymeric Cytoskeletal Fiber
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