AHNAK2 and PRAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AHNAK2	PRAP1
Description		AHNAK nucleoprotein 2	proline rich acidic protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane T-tubule Sarcolemma	Extracellular Region Endoplasmic Reticulum
	Molecular Function	Protein Binding	Protein Binding Lipid Binding Triglyceride Binding
	Biological Process	Regulation Of RNA Splicing	DNA Damage Response DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Apoptotic Process Cellular Response To X-ray Deactivation Of Mitotic Spindle Assembly Checkpoint Positive Regulation Of Intestinal Lipid Absorption Positive Regulation Of Triglyceride Transport Positive Regulation Of Phospholipid Transport
Pathways
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Rheumatoid arthritis ( 24390342 30423114) Systemic lupus erythematosus ( 26663301 33272962)	Nonunion in individuals with fractures ( 30680360)
Interacting Genes		16 interacting genes: ABLIM2 ASGR1 C3orf52 CTSA CYB5B CYBC1 FAM3C GABARAPL1 GABARAPL2 IGFBP5 PRAP1 SUMO2 TSPO2 UBIAD1 VAMP3 ZFPL1	11 interacting genes: AHNAK2 ASPH CEP19 GRB2 HSPA6 MEOX2 MRFAP1 SGTA SGTB UBQLN1 UBQLN2
Entrez ID		113146	118471
HPRD ID		12261	17898
Ensembl ID		ENSG00000185567	ENSG00000165828
Uniprot IDs		Q8IVF2	A6XND8 Q96NZ9
PDB IDs		4CN0
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Endoplasmic Reticulum Phosphatidylethanolamine Binding GABA Receptor Binding Negative Regulation Of Skeletal Muscle Hypertrophy Beta-tubulin Binding Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process Organelle Membrane Positive Regulation Of Triglyceride Transport 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity Autophagosome Maturation Autophagosome Membrane	TRC Complex Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteolysis Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Targeting To ER COP9 Signalosome Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Proteasomal Protein Catabolic Process Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Protein Catabolic Process Response To Endoplasmic Reticulum Stress Guanyl-nucleotide Exchange Factor Adaptor Activity Negative Regulation Of Store-operated Calcium Channel Activity Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment Cytoplasm Protein Targeting To Membrane Positive Regulation Of Protein Metabolic Process Peptidyl-aspartic Acid 3-dioxygenase Activity Regulation Of Transmembrane Transporter Activity Roof Of Mouth Development Regulation Of Monoatomic Ion Transmembrane Transporter Activity Grb2-EGFR Complex Autophagosome Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Protein Catabolic Process Autophagosome Assembly Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Cellular Response To Stress Autophagosome Organization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway BAT3 Complex Binding Negative Regulation Of Clathrin-dependent Endocytosis Vesicle Targeting, To, From Or Within Golgi Activation Of Store-operated Calcium Channel Activity Identical Protein Binding Somite Specification Proteasomal Protein Catabolic Process Positive Regulation Of Store-operated Calcium Channel Activity Regulation Of Calcium Ion Transmembrane Transport Neurotrophin TRKA Receptor Binding Cellular Heat Acclimation Regulation Of Cellular Response To Stress Negative Regulation Of ERAD Pathway
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