MSLN and CPLANE2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		MSLN	CPLANE2
Description		mesothelin	ciliogenesis and planar polarity effector complex subunit 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Lumen Golgi Apparatus Plasma Membrane Cell Surface Membrane Side Of Membrane	Cytoplasm Centriole Cytoskeleton Cilium Ciliary Transition Zone Ciliary Basal Body Cell Projection Ciliary Base
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Cell Adhesion Cell-matrix Adhesion	Endocardial Cushion Fusion Exocytosis Smoothened Signaling Pathway Intracellular Protein Localization Regulation Of Smoothened Signaling Pathway Protein Transport Protein Processing Regulation Of Exocytosis Cell Projection Organization Regulation Of Vesicle Fusion Axoneme Assembly Limb Development Cilium Assembly Cranial Skeletal System Development
Pathways		Post-translational modification: synthesis of GPI-anchored proteins Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Amatuximab
Diseases
GWAS		Body mass index ( 26426971) Serum cancer antigen 125 (CA 125) levels ( 31666285)
Interacting Genes		3 interacting genes: APPBP2 CPLANE2 MUC16	5 interacting genes: FUZ IMPDH2 MSLN RND3 TMEM14C
Entrez ID		10232	79363
HPRD ID		03030	14399
Ensembl ID		ENSG00000102854	ENSG00000132881
Uniprot IDs		Q13421	Q9BU20
PDB IDs		4F3F 7U8C 7U9J 7UED 8CX3 8CXC 8CYH 8CZ8 8FSL 8VM1
Enriched GO Terms of Interacting Partners?			IMP Dehydrogenase Activity Regulation Of Heme Biosynthetic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Negative Regulation Of Neural Crest Formation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?