CENPO and CENPP

Number of citations of the paper that reports this interaction (PMID 16622420)
129

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		CENPO	CENPP
Gene Name		centromere protein O	centromere protein P
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleoplasm Cytosol	Chromosome, Centromeric Region Nucleoplasm Cytosol
	Molecular Function
	Biological Process	Mitotic Cell Cycle Nucleosome Assembly CENP-A Containing Nucleosome Assembly	Mitotic Cell Cycle Nucleosome Assembly CENP-A Containing Nucleosome Assembly
Pathways		Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Height ( 23563607) Type 1 diabetes ( 21980299)
Protein-Protein Interactions		5 interactors: CENPP CEP170P1 ERI3 FOS NECAB2	9 interactors: CCDC33 CENPO GOLGA2 KLC3 NHLH1 RPIA TEX11 USHBP1 ZNF341
Entrez ID		79172	401541
HPRD ID		14414	17989
Ensembl ID		ENSG00000138092
Uniprot IDs		Q9BU64	B3KRA5 Q6IPU0 Q7Z672
PDB IDs
Enriched GO Terms of Interacting Partners?		Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Conditioned Taste Aversion RRNA 3'-end Processing Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Sleep Response To Gravity Maturation Of 5.8S RRNA Response To Immobilization Stress CENP-A Containing Nucleosome Assembly Positive Regulation Of Osteoclast Differentiation RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Histone Exchange Response To Corticosterone DNA Replication-independent Nucleosome Assembly Response To Mineralocorticoid Centromere Complex Assembly Cellular Response To Calcium Ion Response To Progesterone Positive Regulation Of Myeloid Leukocyte Differentiation Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway SMAD Protein Signal Transduction Response To Cold Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Skeletal Muscle Cell Differentiation Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway DNA Methylation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway ATP-dependent Chromatin Remodeling Toll-like Receptor 3 Signaling Pathway Regulation Of Osteoclast Differentiation
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